19716-69-9

Basic information

• Product Name: protoberberine
• Synonyms: protoberberine;5,6-Dihydrodibenzo[a,g]quinolizinium
• CAS NO: 19716-69-9
• Molecular Formula: C17H14 N
• Molecular Weight: 0
• Mol File: 19716-69-9.mol
• Article Data: 0

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: g/cm³
• CAS DataBase Reference: protoberberine(CAS DataBase Reference)
• NIST Chemistry Reference: protoberberine(19716-69-9)
• EPA Substance Registry System: protoberberine(19716-69-9)

Safety Data

• Hazardous Substances Data: 19716-69-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C17H14N/c1-2-7-15-12-18-10-9-13-5-3-4-8-16(13)17(18)11-14(15)6-1/h1-8,11-12H,9-10H2/q+1

Related news

Amplification of DNA-binding affinities of protoberberine (cas 19716-69-9) alkaloids by appended polyamines09/08/2019

This communication describes a synthetic approach toward the amplification of the moderate DNA-binding affinities of protoberberine alkaloids. Specifically, three protoberberine derivatives bearing two to six primary amino groups at the 3- and 9-positions of protoberberine were synthesized and c...detailed

Original articleSynthesis, structure and DNA cleavage studies of coumarin analogues of tetrahydroisoquinoline and protoberberine (cas 19716-69-9) alkaloids09/07/2019

Novel molecular matrices have been derived from coumarin-4-acetic acids and β-phenylethylamines using the Bischler–Napieralski protocol which has led to the synthesis of analogues of tetrahydropapaverine in which the dimethoxybenzene moiety has been replaced by substituted coumarins. One carbo...detailed

protoberberine (cas 19716-69-9) Alkaloids09/06/2019

Publisher SummaryThis chapter presents chemotaxonomic compilation of protoberberine alkaloids, 13C NMR data of the protoberberine alkaloids and discusses biological activity of the protoberberine alkaloids. The protoberberine alkaloids are comprised of a tetracyclic ring system, which is based o...detailed

Application of quantitative 1H NMR for the calibration of protoberberine (cas 19716-69-9) alkaloid reference standards09/05/2019

Quantitative nuclear magnetic resonance spectroscopy (qNMR) has been developed into an important tool in the drug analysis, biomacromolecule detection, and metabolism study. Compared with mass balance method, qNMR method bears some advantages in the calibration of reference standard (RS): it det...detailed

ReviewQuaternary protoberberine (cas 19716-69-9) alkaloids09/03/2019

This contribution reviews some general aspects of the quaternary iminium protoberberine alkaloids. The alkaloids represent a very extensive group of secondary metabolites with diverse structures, distribution in nature, and biological effects. The quaternary protoberberine alkaloids (QPA), deriv...detailed

Epiberberine, a natural protoberberine (cas 19716-69-9) alkaloid, inhibits urease of Helicobacter pylori and jack bean: Susceptibility and mechanism09/02/2019

In our previous study, Rhizoma Coptidis extract was found to exert more potent inhibitory effect than its major component berberine towards urease from Helicobacter pylori (HPU) and jack bean (JBU). In continuation of our work, the present study was designed to further comparatively investigate ...detailed

protoberberine (cas 19716-69-9) compounds extracted from Chelidonium majus L. as novel natural photosensitizers for cancer therapy08/31/2019

BackgroundIt has been shown that secondary metabolites occur in Chelidonium majus L. (C. majus) crude extract and milky sap (alkaloids such as berberine, coptisine, chelidonine, chelerythrine, sanguinarine, and protopine) are biologically active compounds with a wide spectrum of pharmacological ...detailed