19717-43-2

Basic information

• Product Name: 1,2-bis(4-bromophenyl)hydrazine
• CAS NO: 19717-43-2
• Molecular Formula: C₁₂H₁₀Br₂N₂
• Molecular Weight: 342.0292
• Mol File: 19717-43-2.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 319.8°C at 760 mmHg
• Flash Point: 147.2°C
• Density: 1.813g/cm³
• Vapor Pressure: 0.000331mmHg at 25°C
• Refractive Index: 1.736
• CAS DataBase Reference: 1,2-bis(4-bromophenyl)hydrazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-bis(4-bromophenyl)hydrazine(19717-43-2)
• EPA Substance Registry System: 1,2-bis(4-bromophenyl)hydrazine(19717-43-2)

Safety Data

• Hazardous Substances Data: 19717-43-2(Hazardous Substances Data)

Usage

Chemical structure

1,2-bis(4-bromophenyl)hydrazine is an organic compound with two 4-bromophenyl groups attached to a hydrazine molecule.

Pharmaceutical research and development

It is used in the research and development of pharmaceuticals.

Organic synthesis

It is utilized in organic synthesis processes.

Anti-cancer properties

It is being studied for its potential anti-cancer properties.

Anti-inflammatory properties

It is also being investigated for its potential anti-inflammatory properties.

Industrial and materials science applications

Due to its chemical structure and reactivity, 1,2-bromophenyl)hydrazine may have uses in materials science and industry.

Safety precautions

It is important to handle this chemical with caution and follow proper safety protocols due to its potential hazards.

Upstream product

• 1601-98-5 1,2-bis(4-bromophenyl)diazene 
• 586-78-7 para-nitrophenyl bromide 
• 1215-42-5 1,2-bis(4-bromophenyl)diazene oxide 
• 64-17-5 ethanol 
• 64-19-7 acetic acid 
• 1601-98-5 (E)-bis(4-bromophenyl)diazene 
• 73183-34-3 bis(pinacol)diborane 
• 106-40-1 4-bromo-aniline 
• 34139-26-9 4-nitrohydrazobenzene 
• 122-66-7 diphenyl hydrazine 

Downstream Products

• 1601-98-5 1,2-bis(4-bromophenyl)diazene 
• 106-40-1 4-bromo-aniline 
• 74763-66-9 1,2-bis(4-bromophenyl)-1,2-dimethylhydrazine 
• 1601-98-5 (E)-bis(4-bromophenyl)diazene 
• 34139-26-9 4-nitrohydrazobenzene 
• 17082-12-1 trans-azobenzene 

Relevant articles and documents

Visible-Light-Promoted Diboron-Mediated Transfer Hydrogenation of Azobenzenes to Hydrazobenzenes

A visible-light-promoted transfer hydrogenation of azobenzenes has been developed. In the presence of B2pin2 and upon visible-light irradiation, the reactions proceeded smoothly in methanol at ambient temperature. The azobenzenes with diverse functional groups have been reduced to the corresponding hydrazobenzenes with a yield of up to 96%. Preliminary mechanistic studies indicated that the hydrogen atom comes from the solvent and the transformation is achieved through a radical pathway.

Tandem selective reduction of nitroarenes catalyzed by palladium nanoclusters

We report a catalytic tandem reduction of nitroarenes by sodium borohydride (NaBH4) in aqueous solution under ambient conditions, which can selectively produce five categories of nitrogen-containing compounds: anilines, N-aryl hydroxylamines, azoxy-, azo- and hydrazo-compounds. The catalyst is in situ-generated ultrasmall palladium nanoclusters (Pd NCs, diameter of 1.3 ± 0.3 nm) from the reduction of Pd(OAc)2 by NaBH4. These highly active Pd NCs are stabilized by surface-coordinated nitroarenes, which inhibit the further growth and aggregation of Pd NCs. By controlling the concentration of Pd(OAc)2 (0.1-0.5 mol% of nitroarene) and NaBH4, the water/ethanol solvent ratio and the tandem reaction sequence, each of the five categories of N-containing compounds can be obtained with excellent yields (up to 98%) in less than 30 min at room temperature. This tunable catalytic tandem reaction works efficiently with a broad range of nitroarene substrates and offers a green and sustainable method for the rapid and large-scale production of valuable N-containing chemicals.

Transfer Hydrogenation of Azo Compounds with Ammonia Borane Using a Simple Acyclic Phosphite Precatalyst

Tris(quinolin-8-yl)phosphite, P(Oquin)3, promotes the dehydrogenation of H3N·BH3 (AB) and the transfer hydrogenation of azoarenes using ammonia borane (AB) as H2 source. The metal-free reduction of azoarenes proceeds under mild reaction conditions upon which several diphenylhydrazine derivatives are obtained in high yields. The reactivity of P(Oquin)3 toward AB was evaluated through NMR in situ tests. The rate of the reaction, activation parameters, deuterium kinetic isotope effect (DKIE) and linear-free energy relationship were investigated. Such mechanistic and kinetic studies suggest that P(Oquin)3 is a precatalyst and that AB is likely involved in more than one stage of the reaction pathway. Furthermore, the kinetic data indicate that the reaction proceeds through an ordered transition state, possibly associative.