19901-15-6

Basic information

• Product Name: ACETALDEHYDE-2,2,2-D3
• Synonyms: ACETALDEHYDE-2,2,2-D3;CD3CHO;ACETALDEHYDE-2,2,2-D3, 98 ATOM % D;ACETALDEHYDE-2,2,2-D3 98%;Acetaldehyde--d3;2,2,2-trideuterioacetaldehyde
• CAS NO: 19901-15-6
• Molecular Formula: C₂H₄O
• Molecular Weight: 47.07
• Product Categories: A;Alphabetical Listings;Stable Isotopes
• Mol File: 19901-15-6.mol
• Article Data: 10

Chemical Properties

• Melting Point: −125 °C(lit.)
• Boiling Point: 21 °C(lit.)
• Flash Point: <−30 °F
• Appearance: /
• Density: 0.838 g/mL at 25 °C
• Vapor Pressure: 965mmHg at 25°C
• Refractive Index: n20/D 1.332(lit.)
• Storage Temp.: 0-6°C
• CAS DataBase Reference: ACETALDEHYDE-2,2,2-D3(CAS DataBase Reference)
• NIST Chemistry Reference: ACETALDEHYDE-2,2,2-D3(19901-15-6)
• EPA Substance Registry System: ACETALDEHYDE-2,2,2-D3(19901-15-6)

Safety Data

• Hazard Codes: F+,Xn
• Statements: 12-36/37-40
• Safety Statements: 16-33-36/37
• RIDADR: UN 1089 3/PG 1
• WGK Germany: 3
• Hazardous Substances Data: 19901-15-6(Hazardous Substances Data)

Usage

Description

ACETALDEHYDE-2,2,2-D3 is a deuterated compound of acetaldehyde, which is a widely used chemical in various fields due to its unique properties. It is characterized by the presence of three deuterium atoms (2H or D), which replace the hydrogen atoms in the molecule. This substitution can significantly alter the chemical and physical properties of the compound, making it suitable for specific applications in research and industry.

Uses

Used in Medical and Pharmaceutical Research:
ACETALDEHYDE-2,2,2-D3 is used as a derivatizing agent for the measurement of endogenous epinephrine and norepinephrine in human plasma. This application is crucial in understanding the levels of these neurotransmitters, which play a vital role in the body's stress response and other physiological functions. The use of deuterated acetaldehyde allows for more accurate and reliable quantification of these compounds in biological samples.
Used in Neurochemistry and Neurotransmitter Research:
ACETALDEHYDE-2,2,2-D3 is also utilized to label the amine groups on biogenic monoamine neurotransmitters for simultaneous panel determination. This application is essential in studying the interactions and functions of various neurotransmitters in the nervous system. The deuterated compound provides a unique and specific label that can be easily detected and distinguished from other molecules, facilitating the analysis of complex neurotransmitter systems.

InChI:InChI=1/C2H4O/c1-2-3/h2H,1H3/i1D3

Upstream product

• 2875-96-9 1,1,1,3,3,3-hexadeuteriopropane 
• 811-98-3 d⁽⁴⁾-methanol 
• 201230-82-2 carbon monoxide 
• 1759-87-1 2,2,2-trideuteroethanol 
• 1455-13-6 deuteromethanol 
• 75-07-0 acetaldehyde 
• 92144-49-5 acetaldehyde-2,2,2-d3 diethyl acetal 
• 2206-26-0 [D₃]acetonitrile 

Downstream Products

• 22544-43-0 <1,2,2,2-D4>Ethanol 

Relevant articles and documents

Heptakis-6-amino-6-deoxy-β-cyclodextrin as a catalyst for H/D exchange

Heptakis-6-amino-6-deoxy-β-cyclodextrin 2 at pD = 6.50, 20°C catalyzes CH/CD exchange in malonic acid, pyruvic acid and acetaldehyde. Accelerations as large as 3800 were observed. Copyright (C) 1996 Elsevier Science Ltd.

Selective oxidation of ethanol to acetaldehyde on gold

We present results from an investigation of the oxidative conversion of ethanol into acetaldehyde on Au(111) employing temperature-programmed desorption (TPD) and molecular beam reactive scattering (MBRS). Results from isotopic experiments show that ethan

Are Tetrahedral Intermediates Formed by Addition of Nucleophiles to Organoboranes in the Gas Phase?

Nucleophilic addition of CD3O- to Me2BOMe gives the same addition product as the corresponding reaction between Me2BOCD3 and MeO-, as evidenced by the identical collisional activation mass spectra of the products.This is interpreted in terms of exclusive formation of a boron product ion of terahedral geometry.The decompositions of the product involve loss of MeOH and CD3OH and the formation of MeO- and CD3O-.The major decompositions of (CD3)3B+-OCH2CH2XMe (X=O, S, or NMe2) are similar to those outlined above and may be explained by initial formation of (CD3)3B-OCH2CH2XMe.However, there are some unusual fragmentations (e.g. loss of CH3D) which may occur through the alternative structure (CD3)3B-X+(Me)CH2CH2O-.It is suggested the other ambident species may also react with Me3B to form several tetrahedral species, e.g. deprotonated methyl acetate could yield Me3B-CH2CO2Me, Me3B-OC(OMe)=CH2, and Me3B--O+(Me)CCH2O-.The formation of the third structure is supported by the pronounced loss of ketene from this system.