19968-19-5 Usage
Description
1H-Pyrazole, 3,4-bis(trifluoromethyl)is a chemical compound with the molecular formula C5H3F6N3. It is an organofluorine compound that consists of a pyrazole ring with two trifluoromethyl groups attached at the 3 and 4 positions. 1H-Pyrazole, 3,4-bis(trifluoromethyl)is known for its strong electron-withdrawing capability due to the presence of the trifluoromethyl groups, making it useful in various chemical reactions and applications.
Uses
Used in Chemical Reactions:
1H-Pyrazole, 3,4-bis(trifluoromethyl)is used as a reagent in chemical reactions for its strong electron-withdrawing capability, which can influence the reactivity and selectivity of the reactions.
Used in Synthesis of Complex Organic Molecules:
1H-Pyrazole, 3,4-bis(trifluoromethyl)is used as a building block in the synthesis of complex organic molecules due to its unique properties and reactivity, allowing for the creation of a wide range of compounds with diverse applications.
Used in Pharmaceutical Industry:
1H-Pyrazole, 3,4-bis(trifluoromethyl)is used as a key intermediate in the development of new pharmaceuticals, leveraging its electron-withdrawing nature and reactivity to create novel drug candidates with potential therapeutic benefits.
Used in Material Science:
The presence of trifluoromethyl groups in 1H-Pyrazole, 3,4-bis(trifluoromethyl)makes it valuable in the development of new materials, where its electron-withdrawing properties can contribute to the desired characteristics of the materials being developed.
Used in Drug Discovery:
1H-Pyrazole, 3,4-bis(trifluoromethyl)is utilized in drug discovery processes, where its unique structural features and reactivity can lead to the identification of new drug candidates with improved pharmacological properties.
Check Digit Verification of cas no
The CAS Registry Mumber 19968-19-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,9,6 and 8 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 19968-19:
(7*1)+(6*9)+(5*9)+(4*6)+(3*8)+(2*1)+(1*9)=165
165 % 10 = 5
So 19968-19-5 is a valid CAS Registry Number.
19968-19-5Relevant articles and documents
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Kobayashi et al.
, p. 867 (1977)
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"Reported, but still unknown." A closer look into 3,4-bis- and 3,4,5-tris(trifluoromethyl)pyrazoles
Gerus, Igor I.,Mironets, Roman V.,Kondratov, Ivan S.,Bezdudny, Andrei V.,Dmytriv, Yurii V.,Shishkin, Oleg V.,Starova, Viktoriia S.,Zaporozhets, Olga A.,Tolmachev, Andrey A.,Mykhailiuk, Pavel K.
, p. 47 - 56 (2012/03/10)
Straightforward practical synthetic approaches to 3,4-bis- and 3,4,5-tris(trifluoromethyl)pyrazoles have been developed. The key step of the both syntheses is a transformation of the carboxylic group in a pyrazole core into the trifluoromethyl group by sulfur tetrafluoride. The elaborated synthetic protocols allow gram-scale preparation of the target products. The obtained compounds are comprehensively characterized by means of crystallographic analysis, determination of pKa values and fluorescence measurements.
