199733-66-9Relevant articles and documents
Synthesis of 3',5'-dithymidylyl-α-hydroxyphosphonate dimer building blocks for oligonucleotide synthesis - A new pro-oligonucleotide approach
Mauritz, Ralf P.,Meier, Chris,Uhlmann, Eugen
, p. 1209 - 1212 (2007/10/03)
The synthesis of the dimer building blocks 1 and 2 and their introduction into (T)15-oligonucleotides is described. The stability against 3'-exonuclease digestion (SVP) as well as the hybridization properties (T(m) values) were examined.