200938-58-5

Basic information

• Product Name: 6-iodo-3-propyl-2-thioxo-2,3-dihydroquinazolin-4(1H)-one
• Synonyms: 6-iodo-3-propyl-2-thioxo-2,3-dihydroquinazolin-4(1H)-one;2,3-Dihydro-6-iodo-3-propyl-2-thioxo-4(1H)-quinazolinone
• CAS NO: 200938-58-5
• Molecular Formula: C₁₁H₁₁IN₂OS
• Molecular Weight: 346
• EINECS: 1533716-785-6
• Mol File: 200938-58-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 430.827 °C at 760 mmHg
• Flash Point: 214.356 °C
• Appearance: /
• Density: 1.83 g/cm³
• CAS DataBase Reference: 6-iodo-3-propyl-2-thioxo-2,3-dihydroquinazolin-4(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-iodo-3-propyl-2-thioxo-2,3-dihydroquinazolin-4(1H)-one(200938-58-5)
• EPA Substance Registry System: 6-iodo-3-propyl-2-thioxo-2,3-dihydroquinazolin-4(1H)-one(200938-58-5)

Safety Data

• Hazardous Substances Data: 200938-58-5(Hazardous Substances Data)

Usage

General Description

"6-iodo-3-propyl-2-thioxo-2,3-dihydroquinazolin-4(1H)-one" is a chemical compound with the molecular formula C12H13IN2OS. It is a quinazolinone derivative with a iodine atom at the 6th position, and a propyl group at the 3rd position. The presence of a thioxo group and a dihydroquinazolinone ring structure gives this compound unique chemical properties. It may have potential applications in pharmaceutical research and drug development due to its structural features and potential biological activities. Further investigation into its properties and potential uses could be beneficial for the scientific community.

Upstream product

• 541-41-3 chloroformic acid ethyl ester 
• 5326-47-6 2-amino-5-iodobenzoic acid 
• 628-30-8 n-Propyl isothiocyanate 
• 927-67-3 propylthiourea 

Relevant articles and documents

Preparation method of 2-thioxo-2,3-dihydroquinazoline-4(1H)-one compound

The invention discloses a preparation method of a 2-thioxo-2,3-dihydroquinazoline-4(1H)-one compound. The preparation method of the compound of formula I includes the following steps: a compound of formula II and a compound of formula III are subjected to a condensation reaction in an organic solvent under the action of an organic base to obtain the compound of the formula I, wherein the reactiontemperature is 70-155 DEG C, X1, X2, X3 and X4 are independently hydrogen or halogen, and R is hydrogen or one of alkyl groups of C1-C4. The preparation method provided by the invention is mild in conditions, environment-friendly, low in cost, high in yield, simple and efficient, and is suitable for industrial production. The formula of the reaction is shown in the description.