201002-47-3 Usage
Description
FMOC-D-LYS-OH HCL, also known as Nα-Fmoc-D-lysine hydrochloride, is an N-Fmoc-protected form of D-Lysine, which is the unnatural isomer of L-Lysine. It is a white to off-white powder that has the ability to reduce non-enzymatic glycation in vitro. D-Lysine also exists as polypeptide chains of poly-D-lysine, a nonspecific adhesion-promoting molecule that has the potential to be a polymeric drug carrier.
Uses
Used in Pharmaceutical Industry:
FMOC-D-LYS-OH HCL is used as a building block for the synthesis of peptides and peptidomimetics for various pharmaceutical applications. Its N-Fmoc protection allows for selective deprotection and coupling reactions during peptide synthesis, enabling the creation of complex peptide structures.
Used in Drug Delivery Systems:
FMOC-D-LYS-OH HCL is used as a component in the development of polymeric drug carriers, such as poly-D-lysine, which can be utilized for targeted drug delivery and controlled release of therapeutic agents. The nonspecific adhesion-promoting properties of poly-D-lysine make it a promising candidate for enhancing the effectiveness of drug delivery systems.
Used in Research and Development:
FMOC-D-LYS-OH HCL is used as a research tool for studying the properties and applications of D-amino acids and their derivatives. Its ability to reduce non-enzymatic glycation makes it a valuable compound for investigating the role of glycation in various biological processes and diseases.
Used in Chemical Synthesis:
FMOC-D-LYS-OH HCL is used as an intermediate in the synthesis of various chemical compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals. Its versatility as a building block allows for the development of novel compounds with potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 201002-47-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,1,0,0 and 2 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 201002-47:
(8*2)+(7*0)+(6*1)+(5*0)+(4*0)+(3*2)+(2*4)+(1*7)=43
43 % 10 = 3
So 201002-47-3 is a valid CAS Registry Number.
201002-47-3Relevant articles and documents
Investigating d-lysine stereochemistry for epigenetic methylation, demethylation and recognition
Belle, Roman,Al Temimi, Abbas H. K.,Kumar, Kiran,Pieters, Bas J. G. E.,Tumber, Anthony,Dunford, James E.,Johansson, Catrine,Oppermann, Udo,Brown, Tom,Schofield, Christopher J.,Hopkinson, Richard J.,Paton, Robert S.,Kawamura, Akane,Mecinovi?, Jasmin
supporting information, p. 13264 - 13267 (2017/12/26)
Histone lysine methylation is regulated by N?-methyltransferases, demethylases, and N?-methyl lysine binding proteins. Thermodynamic, catalytic and computational studies were carried out to investigate the interaction of three epigen
