201214-53-1 Usage
Description
Methyl 4-acetamido-5-iodo-2-methoxybenzoate is a chemical compound with a molecular formula C11H11IN2O4. It is an ester derivative of 5-iodo-2-methoxybenzoic acid, featuring an acetamido group and a methyl ester group attached to the aromatic ring. methyl 4-acetamido-5-iodo-2-methoxybenzoate has potential applications in organic synthesis and pharmaceutical research, serving as a building block for the synthesis of various biologically active compounds.
Uses
Used in Organic Synthesis:
Methyl 4-acetamido-5-iodo-2-methoxybenzoate is used as a building block in organic synthesis for the creation of various biologically active compounds. Its unique structure allows for the development of new molecules with potential applications in different fields.
Used in Pharmaceutical Research:
In pharmaceutical research, methyl 4-acetamido-5-iodo-2-methoxybenzoate is used as a precursor for the synthesis of drug candidates. Its iodinated and functionalized structure can be further modified to yield compounds with specific therapeutic properties.
Used in Chemical Production:
Methyl 4-acetamido-5-iodo-2-methoxybenzoate is used in the chemical production industry as an intermediate for the synthesis of other complex organic compounds. Its versatility in chemical reactions makes it a valuable component in the production process.
It is important to handle this chemical with care and follow proper safety protocols, as it may pose hazards if not used and stored appropriately.
Check Digit Verification of cas no
The CAS Registry Mumber 201214-53-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,1,2,1 and 4 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 201214-53:
(8*2)+(7*0)+(6*1)+(5*2)+(4*1)+(3*4)+(2*5)+(1*3)=61
61 % 10 = 1
So 201214-53-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H12INO4/c1-6(14)13-9-5-10(16-2)7(4-8(9)12)11(15)17-3/h4-5H,1-3H3,(H,13,14)
201214-53-1Relevant articles and documents
Synthesis and evaluation of novel radioiodinated benzamides for malignant melanoma
Pham, Tien Q.,Greguric, Ivan,Liu, Xiang,Berghofer, Paula,Ballantyne, Patrice,Chapman, Janette,Mattner, Filomena,Dikic, Branko,Jackson, Timothy,Loc'h, Christian,Katsifis, Andrew
, p. 3561 - 3572 (2008/02/09)
The imaging potential of a series of [123I]benzamides was studied in mice bearing B16F0 melanoma tumors. Compound [123I]25 exhibited tumor uptake >8 %ID/g at 1 h, while that of [123I]14d and [123I]25 reached a maximum of 9-12 %ID/g at 6 h. Standardized uptake values of [123I]14d were higher than 100 between 24 and 72 h after injection. In haloperidol treated animals, the tumor uptake of [ 123I]14d was not significantly different to controls, while significant reduction of [123I]25 uptake was observed, supporting that [123I]14d uptake relates to melanin interaction, whereas part of the mechanism of [123I]25 uptake is related to its σ1-receptor affinity. Benzamides 14d and 25, which display rapid and high tumor uptake, appear to be promising imaging agents for melanoma detection, while 14d, which displays a long lasting and high melanoma/nontarget ratio, is more suitable for evaluation as a potential radiotherapeutic.
