2013-84-5Relevant articles and documents
KOtBu-Mediated Aerobic Transition-Metal-Free Regioselective β-Arylation of Indoles: Synthesis of β-(2-/4-Nitroaryl)-indoles
Kumar, Shailesh,Rathore, Vandana,Verma, Ajay,Prasad, Ch. Durga,Kumar, Amit,Yadav, Abhimanyu,Jana, Sadhan,Sattar, Moh,Meenakshi,Kumar, Sangit
, p. 82 - 85 (2014)
A KOtBu-mediated intermolecular oxidative C-C coupling of nitroarenes with indoles is presented in DMSO at room temperature in an open flask. By using this mild and economical methodology, syntheses of β-(2/4-nitroaryl)-indoles with sensitive f
First heterogeneously palladium-catalysed fully selective C3-arylation of free NH-indoles
Cusati, Giuseppe,Djakovitch, Laurent
, p. 2499 - 2502 (2008/09/19)
A simple heterogeneously palladium-catalysed procedure for the selective C3-arylation of indoles is reported. Under relatively standard reaction conditions (Pd-catalyst, K2CO3, dioxane, reflux), using only 1 mol % [Pd(NH3)4]/NaY as the catalyst, indoles substituted or not at position 2 gave up to 92% conversion (i.e., 85% isolated yield) towards the expected C3-arylated indole.