20150-34-9 Usage
Description
Ferrous Bisglycinate, also known as Iron Bisglycinate, is an iron-amino acid chelate where iron is bound to the amino acid and glycine. This unique structure protects the iron from the action of absorption inhibitors, enhancing its bioavailability. Ferrous Bisglycinate is the major amino acid chelate produced commercially, with a patented compound manufactured by Albion Laboratories, Utah, USA, being used in most published studies. The chelate is formed by two glycine molecules combining with ferrous iron in a double heterocyclic ring structure, which suggests that iron is protected from inhibitors, resulting in higher absorption rates compared to ferrous sulfate.
Uses
Used in Nutraceutical Applications:
Ferrous Bisglycinate is used as a nutraceutical ingredient to address iron deficiency and improve overall health. Its high bioavailability makes it an effective iron supplement, particularly for individuals with low iron levels or those who need additional iron intake for various health reasons.
Used in Infant Formulas and Food Fortification:
Ferrous Bisglycinate is used as an additive in the fortification of infant formulations and foods to ensure adequate iron intake, especially for infants and young children who are at a higher risk of developing iron deficiency. The chelate's enhanced bioavailability and protection from absorption inhibitors make it an ideal choice for fortifying these products, promoting healthy growth and development in infants.
Food additive
Amino acid chelates are recommended for milk and beverage products. Ferrous bisglycinate has Generally Recognized as Safe (GRAS) status but is relatively expensive and readily promotes fat oxidation in cereal foods unless an anti-oxidant is added, and causes undesirable color reactions in some foods. Four non controlled efficacy studies with ferrous bisglycinate fortified foods have reported a marked decrease in the prevalence of anemia or iron deficiency anemia in children or adolescents. Three studies made in Brazil reported good efficacy in fortified liquid milk, sweetened bread rolls and a whey based beverage, and a fourth study in Saudi Arabia reported good efficacy in an iron fortified flavored milk drink. Recently, fer- rous bisglycinate fortified bread made from high extraction flour resulted in small but significant increases in both hemoglobin and serum ferritin when fed in a randomized controlled design to South African schoolchildren. A longer feeding period with higher iron concentrations would probably have given more impressive results. The influence of ferrous bisglycinate on stored flour was not investigated in this study. The main disadvantage of ferrous bisglycinate is its high cost. A recent cost analysis showed the cost of ferrous bisglycinate, taking bioavailability into account, to be 7–18 times that of ferrous sulfate.
Food additive
Ferrous bisglycinate is well suited to the fortification of liquid whole milk and other dairy products where the use of ferrous sulfate causes rancidity off-flavours. However, ferrous bisglycinate can also cause rancidity by oxidizing fats in food, which can be a problem in cereal flours and weaning cereals unless an antioxidant is added as well. Furthermore, the bisglycinate is much more expensive than many other iron compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 20150-34-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,1,5 and 0 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 20150-34:
(7*2)+(6*0)+(5*1)+(4*5)+(3*0)+(2*3)+(1*4)=49
49 % 10 = 9
So 20150-34-9 is a valid CAS Registry Number.
20150-34-9Relevant articles and documents
Iron (II) amino acid chelates with reducing agents attached thereto
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Page/Page column 5, (2008/06/13)
The present invention is drawn to compositions and methods that include iron (II) amino acid chelate having a reducing agent bonded thereto. The reducing agent can be configured to substantially maintain the iron (II) in its ferrous oxidation state. The iron (II) amino acid chelate can have an amino acid ligand to iron (II) molar ratio from 1:1 to 2:1 and a reducing agent ligand to iron (II) molar ratio from 1:1 to 4:1, with a proviso that the combination of the amino acid ligands and the reducing agent ligands satisfies from 3 to 6 of the coordination sites of the iron (II).
