202061-61-8

Basic information

• Product Name: 2-phenylpropanohydroximoyl chloride
• Synonyms: 2-phenylpropanohydroximoyl chloride
• CAS NO: 202061-61-8
• Molecular Weight: 183.637
• Mol File: 202061-61-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-phenylpropanohydroximoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenylpropanohydroximoyl chloride(202061-61-8)
• EPA Substance Registry System: 2-phenylpropanohydroximoyl chloride(202061-61-8)

Safety Data

• Hazardous Substances Data: 202061-61-8(Hazardous Substances Data)

Upstream product

• 34713-70-7 2-Phenylpropanal 
• 5153-67-3 nitrostyrene 
• 917-54-4 methyllithium 
• 59647-78-8 2-phenylpropanal oxime 

Downstream Products

• 1318073-02-7 ethyl 5-methyl-3-(1-phenylethyl)isoxazole-4-carboxylate 
• 1219938-40-5 3-(1-phenyl-ethyl)-1,2-benzisoxazole 
• 24277-44-9 (1-isothiocyanato-ethyl)-benzene 
• 28164-33-2 1,4-diphenylpent-1-yn-3-one oxime 

Relevant articles and documents

An efficient one-pot synthesis of 3-aryl-5-methylisoxazoles from aryl aldehydes

An efficient protocol for the one-pot preparation of alkyl 3-aryl-5-methylisoxazole-4-carboxylates from aryl aldehydes is described. This method is readily amenable to the large scale preparation of isoxazoles as well as the parallel synthesis of isoxazole libraries.

A facile one-pot preparation of isothiocyanates from aldoximes

Isothiocyanates 2a-l were prepared in excellent yields in a one-pot reaction from aldoxime derivatives 1a-l by successive treatment of aldoxime with N-chlorosuccinimide (NCS), thiourea, and triethylamine. The use of HCl/DMF/Oxone system in the reaction instead of NCS was equally effective.