20280-81-3 Usage
General Description
4-Methoxycoumarin, also known as methoxsalen, is a naturally occurring compound found in the leaves and roots of various plants such as the Ammi majus. It is commonly used in the medical field as a photosensitizing agent, particularly in phototherapy treatments for skin disorders such as psoriasis and vitiligo. When exposed to ultraviolet A (UVA) radiation, 4-methoxycoumarin binds to DNA and disrupts its replication, leading to the death of rapidly dividing cells. Due to its ability to sensitize skin to light, 4-methoxycoumarin is also used in combination with ultraviolet light in some cancer treatments to target and destroy malignant cells. Additionally, it has been studied for its potential as an antibacterial and antioxidant agent, with promising results in inhibiting the growth of certain bacteria and scavenging free radicals.
Check Digit Verification of cas no
The CAS Registry Mumber 20280-81-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,2,8 and 0 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 20280-81:
(7*2)+(6*0)+(5*2)+(4*8)+(3*0)+(2*8)+(1*1)=73
73 % 10 = 3
So 20280-81-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H8O3/c1-12-9-6-10(11)13-8-5-3-2-4-7(8)9/h2-6H,1H3
20280-81-3Relevant articles and documents
Reaction of 4-hydroxycoumarin or its O-substituted derivatives with diatomic interhalogens: ICl and IBr
Popa, Marcel Mirel,Draghici, Constantin,Barbu, Loredana,Dumitrescu, Denisa E.,Dumitrascu, Florea
, p. 344 - 350 (2017/02/10)
Herein, we present some aspects regarding the iodination/bromination of 4-hydroxycoumarin or its O-methyl or O-acetyl derivatives with iodine monochloride or iodine monobromide as halogenation reagents. Also, the investigation of photochemical transformation of the three 3-iodocoumarins was investigated for the first time.
