203115-93-9 Usage
Description
2-(3'-FLUOROPHENOXY)PROPANE is an organic compound characterized by its fluorophenoxy group attached to a propane backbone. This structure endows it with unique chemical and physical properties, making it a valuable intermediate in the synthesis of various complex molecules and materials.
Uses
Used in Pharmaceutical Industry:
2-(3'-FLUOROPHENOXY)PROPANE is used as a building block for the preparation of ligands such as EPhos, piperidinemethanols, and functionalized xanthones. These ligands are essential in the development of new drugs and pharmaceutical compounds, contributing to the advancement of medicinal chemistry.
Used in Chemical Synthesis:
In the field of chemical synthesis, 2-(3'-FLUOROPHENOXY)PROPANE serves as a versatile intermediate for the creation of a wide range of compounds. Its fluorophenoxy group can be further modified or reacted with other molecules, allowing for the development of new materials with specific properties and applications.
Used in Material Science:
2-(3'-FLUOROPHENOXY)PROPANE can be utilized in the development of novel materials with tailored properties. Its unique structure can be incorporated into polymers, coatings, or other materials to enhance their performance, such as improving their thermal stability, chemical resistance, or mechanical strength.
Check Digit Verification of cas no
The CAS Registry Mumber 203115-93-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,3,1,1 and 5 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 203115-93:
(8*2)+(7*0)+(6*3)+(5*1)+(4*1)+(3*5)+(2*9)+(1*3)=79
79 % 10 = 9
So 203115-93-9 is a valid CAS Registry Number.
203115-93-9Relevant articles and documents
Mechanistic Insight Leads to a Ligand Which Facilitates the Palladium-Catalyzed Formation of 2-(Hetero)Arylaminooxazoles and 4-(Hetero)Arylaminothiazoles
Olsen, Esben P. K.,Arrechea, Pedro L.,Buchwald, Stephen L.
supporting information, p. 10569 - 10572 (2017/08/22)
By using mechanistic insight, a new ligand (EPhos) for the palladium-catalyzed C?N cross-coupling between primary amines and aryl halides has been developed. Employing an isopropoxy group at the C3-position favors the C-bound isomer of the ligand-supported palladium(II) complexes and leads to significantly improved reactivity. The use of a catalyst system based on EPhos with NaOPh as a mild homogeneous base proved to be very effective in the formation of 4-arylaminothiazoles and highly functionalized 2-arylaminooxazoles. Previously, these were not readily accessible using palladium catalysis.
Practical synthesis of aromatic ethers by SNAr of fluorobenzenes with alkoxides
Rodriguez, Juan R.,Agejas, Javier,Bueno, Ana B.
, p. 5661 - 5663 (2007/10/03)
Aromatic fluorines have been substituted by alkoxides in a variety of activated and unactivated aromatic systems.
