20364-70-9Relevant articles and documents
Cis-selective and highly enantioselective hydrogenation of 2,3,4-trisubstituted quinolines
Zhang, Zhenhua,Du, Haifeng
, p. 2816 - 2819 (2015)
A highly enantioselective cis-hydrogenation of 2,3,4-trisubstituted quinolines has been realized for the first time using chiral borane catalysts generated in situ from chiral dienes. A variety of tetrahydroquinoline derivatives containing three contiguous stereogenic centers were obtained in 76-99% yields with 82-99% ee's.