203662-66-2

Basic information

• Product Name: 2-Cyano-7-azaspiro[3.5]nonane-7-carboxylic acid tert-butyl ester
• Synonyms: 2-Cyano-7-azaspiro[3.5]nonane-7-carboxylic acid tert-butyl ester;7-Boc-2-cyano-7-azaspiro[...;tert-butyl 2-cyano-7-azaspiro[3.5]nonane-7-carboxylate;7-Boc-2-cyano-7-azaspiro[3.5]nonane;2-Cyano-7-azaspiro[3.5]nonane-7-carboxylic acid 1,1-dimethylethyl ester;[7-(tert-butoxycarbonyl)-7-azaspiro[3.5]non-2-yl]carbonitrile;2-Cyano-7-azaspiro[3.5]nonane-7-carboxylic acid tert-butyl ester - C5995
• CAS NO: 203662-66-2
• Molecular Formula: C₁₄H₂₂N₂O₂
• Molecular Weight: 250.33668
• Mol File: 203662-66-2.mol
• Article Data: 12

Chemical Properties

• Melting Point: 65-66.5℃
• Boiling Point: 381.0±42.0 °C(Predicted)
• Appearance: /
• Density: 1.10±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: -1.39±0.40(Predicted)
• CAS DataBase Reference: 2-Cyano-7-azaspiro[3.5]nonane-7-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyano-7-azaspiro[3.5]nonane-7-carboxylic acid tert-butyl ester(203662-66-2)
• EPA Substance Registry System: 2-Cyano-7-azaspiro[3.5]nonane-7-carboxylic acid tert-butyl ester(203662-66-2)

Safety Data

• Hazard Codes: F
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• TSCA: No
• Hazardous Substances Data: 203662-66-2(Hazardous Substances Data)

Usage

General Description

The compound "2-Cyano-7-azaspiro[3.5]nonane-7-carboxylic acid tert-butyl ester" is a chemical substance with a unique structure that consists of a spiro ring system, cyanide group, carboxylic acid tert-butyl ester group and an aza (nitrogen-containing) group. It is a complex organic compound that may be involved in various chemical reactions due to its structural moieties. Its specific properties, synthesis, stability, and uses would depend on these functional groups and the specific reactions they undergo. However, specific information about this compound, including its physical and chemical properties or potential applications, is not readily available, indicating that it may not be a widely studied or commonly used compound.

Upstream product

• 38622-91-2 [(p-methylphenyl)sulfonylmethyl]isonitrile 
• 203661-69-2 tert-butyl 2-oxo-7-azaspiro[3.5]nonane-7-carboxylate 
• 159635-49-1 tert-butyl 4-methylidenepiperidine-1-carboxylate 
• 396653-31-9 tert-butyl 1,1-dichloro-2-oxo-7-azaspiro[3.5]nonane-7-carboxylate 
• 773837-37-9 sodium cyanide 
• 614729-59-8 2-((methylsulfonyl)oxy)-7-azaspiro[3.5]nonane-7-carboxylic acid tert-butyl ester 
• 240401-28-9 2-hydroxy-7-azaspiro[3.5]nonane-7-carboxylic acid tert-butyl ester 

Downstream Products

• 203662-67-3 7-azaspiro[3.5]nonane-2-carbonitrile 
• 203662-68-4 (7-benzyl-7-azaspiro[3.5]non-2-yl)carbonitrile 
• 203662-69-5 methyl (7-benzyl-7-azaspiro[3.5]non-2-yl)carboxylate 
• 873924-12-0 7-(tert-butoxycarbonyl)-7-azaspiro[3.5]nonane-2-carboxylic acid 
• 1160247-15-3 2-aminomethyl-7-aza-spiro[3.5]nonane-7-carboxylic acid tert-butyl ester 

Relevant articles and documents

IRAK DEGRADERS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same.

IRAK DEGRADERS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same.

IRAK DEGRADERS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same. The compounds include an IRAK binding moiety capable of binding to IRAK4 and a degradation inducing moiety (DIM). The DIM could be DTM a ligase binding moiety (LBM) or lysine mimetic. The compounds could be useful as IRAK protein kinase inhibitors and applied to IRAK mediated disorders.