203714-71-0

Basic information

• Product Name: DICHLORO(O-ISOPROPOXYPHENYLMETHYLENE)(TRICYCLOHEXYLPHOSPHINE)RUTHENIUM(II)
• Synonyms: RUTHENIUM, DICHLORO[[2-(1-METHYLETHOXY)PHENYL]METHYLENE](TRICYCLOHEXYLPHOSPHINE);DICHLORO(O-ISOPROPOXYPHENYLMETHYLENE)(TRICYCLOHEXYLPHOSPHINE)RUTHENIUM(II);HOVEYDA-GRUBBS CATALYST 1ST GENERATION;Dichloro[[2-(1-methylethoxy-O)phenyl]methylene](tricyclohexylphosphine)ruthenium;DICHLORO(O-ISOPROPOXYPHENYLMETHYLENE) &;Dichloro(2-isopropoxyphenylmethylene)(tricyclohexylphosphine)ruthenium (II);Hoveyda-Grubbs Catalyst 1st Generation,Dichloro(o-isopropoxyphenylmethylene)(tricyclohexylphosphine)ruthenium(II);RutheniuM,dichloro[[2-(1-Methylethoxy-kO)phenyl]Methylene-kC](tricyclohexylphosphine)-,(SP-5-41)-
• CAS NO: 203714-71-0
• Molecular Formula: C₂₈H₄₅Cl₂OPRu
• Molecular Weight: 600.61
• EINECS: 1312995-182-4
• Product Categories: Ru
• Mol File: 203714-71-0.mol
• Article Data: 2

Chemical Properties

• Melting Point: 195-197 °C(lit.)
• Boiling Point: 383.4oC at 760 mmHg
• Flash Point: 195.6oC
• Appearance: /
• Vapor Pressure: 9.7E-06mmHg at 25°C
• Storage Temp.: 2-8°C
• CAS DataBase Reference: DICHLORO(O-ISOPROPOXYPHENYLMETHYLENE)(TRICYCLOHEXYLPHOSPHINE)RUTHENIUM(II)(CAS DataBase Reference)
• NIST Chemistry Reference: DICHLORO(O-ISOPROPOXYPHENYLMETHYLENE)(TRICYCLOHEXYLPHOSPHINE)RUTHENIUM(II)(203714-71-0)
• EPA Substance Registry System: DICHLORO(O-ISOPROPOXYPHENYLMETHYLENE)(TRICYCLOHEXYLPHOSPHINE)RUTHENIUM(II)(203714-71-0)

Safety Data

• Hazard Codes: F
• Statements: 11
• RIDADR: UN1325 - class 4.1 - PG 2 - Flammable solids, organic, n.o.s., H
• WGK Germany: 3
• Hazardous Substances Data: 203714-71-0(Hazardous Substances Data)

Usage

Uses

Proven to be useful in Ring-Closing Metathesis (RCM) to form macrocycles. Also employed in a pivotal, macrocyclic ring-closing metathesis in the multi-step synthesis of an HCV protease inhibitor.

InChI:InChI=1/C18H33P.C10H12O.2ClH.Ru/c1-4-10-16(11-5-1)19(17-12-6-2-7-13-17)18-14-8-3-9-15-18;1-8(2)11-10-7-5-4-6-9(10)3;;;/h16-18H,1-15H2;3-8H,1-2H3;2*1H;/q;;;;+2/p-2/rC18H33P.C10H12Cl2ORu/c1-4-10-16(11-5-1)19(17-12-6-2-7-13-17)18-14-8-3-9-15-18;1-8(2)13-10-6-4-3-5-9(10)7-14(11)12/h16-18H,1-15H2;3-8H,1-2H3

Upstream product

• 172222-30-9 Grubbs catalyst first generation 
• 67191-35-9 o-isopropoxystyrene 

Downstream Products

• 301224-40-8 [1,3-bis-(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(O-isopropoxyphenylmethylene)ruthenium 

Relevant articles and documents

PROCESS FOR CO-PRODUCING OLEFINS AND DIESTERS OR DIACIDS STARTING FROM UNSATURATED FATS

In order to produce both an olefinic fraction and a composition of diacids or diesters of fats, a process is carried out which comprises, in succession: a) metathesis of an unsaturated fat with ethylene in the presence of at least one non-aqueous ionic liquid; b) separating and recycling the ionic liquid used in the first step; c) separating, by distillation, the olefinic fraction (fraction A) from the unsaturated fat mono-ester or mono-basic acid fraction (fraction B) formed in step a); d) homometathesis of the mono-unsaturated fat ester or acid cut (fraction B) which allows the co-production of unsaturated fat diesters or diacids (fraction C) and ethylene which is recycled to the first methathesis step of the process; and e) optionally, recycling the ionic liquid containing the catalyst used in step d). Of particular application to an oleic sunflower oil, an oleic rapeseed oil or to a mixture of mono-alcohol esters of said oils, whereupon the process can produce both an olefinic fraction (mainly composed of 1-decene) and a composition of diesters or diacids wherein, in general, over half of the chains is constituted by unsaturated C18 chains (mainly composed of octadecene-9 1,18-diacid or diester) and to recycle the ethylene employed.