2038-04-2

Basic information

• Product Name: N-(2-morpholinoethyl)aniline
• Synonyms: N-(2-morpholinoethyl)aniline
• CAS NO: 2038-04-2
• Molecular Weight: 206.288
• Mol File: 2038-04-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: N-(2-morpholinoethyl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-morpholinoethyl)aniline(2038-04-2)
• EPA Substance Registry System: N-(2-morpholinoethyl)aniline(2038-04-2)

Safety Data

• Hazardous Substances Data: 2038-04-2(Hazardous Substances Data)

Usage

Description

N-(2-morpholinoethyl)aniline, also known as N-(2-morpholinoethyl)phenylenediamine, is a chemical compound with the molecular formula C12H18N2O. It is a pale yellow liquid that serves as an important intermediate in various industrial applications.

Uses

Used in Dye and Pigment Industry:
N-(2-morpholinoethyl)aniline is used as an intermediate in the production of dyes and pigments, contributing to the development of colorants for various applications.
Used in Epoxy Resin Industry:
N-(2-morpholinoethyl)aniline is used as a curing agent in the manufacturing of epoxy resins, which are essential for creating strong, durable materials used in coatings, adhesives, and electrical insulation.
Used in Polyurethane Foam Industry:
N-(2-morpholinoethyl)aniline is used as a stabilizer in the production of polyurethane foams, enhancing the stability and performance of these versatile materials used in furniture, insulation, and other applications.

Upstream product

• 110-91-8 morpholine 
• 874-78-2 N-(2-chloroethyl)aniline hydrochloride 
• 3240-94-6 N-(2-chlorethyl)morpholine 
• 62-53-3 aniline 
• 622-40-2 2-(morpholin-4-yl)ethanol 
• 935-06-8 N-(2-chloroethyl)aniline 
• 42802-94-8 4-(2-bromoethyl)morpholine hydrobromide 

Downstream Products

• 92699-34-8 N-(2-morpholin-4-yl-ethyl)-N-phenyl-propionamide 
• 100875-64-7 N-(2-morpholino-ethyl)-acetanilide 
• 102164-31-8 N-(2-morpholino-ethyl)-benzanilide 
• 209333-88-0 8-(4-Benzyloxy-phenyl)-7-oxo-7H-thieno[2,3-a]quinolizine-10-carboxylic acid (2-morpholin-4yl-ethyl)-phenyl-amide 
• 130719-61-8 3-(4-Chlorphenyl)-5-(2-morpholinoethylanilino)isoxazol 
• 130719-57-2 3-(4-Chlorphenyl)-5-(2-morpholinoethylanilino)-4-phenyl-isoxazol 
• 101354-54-5 (2-morpholin-4-yl-ethyl)-phenyl-carbamic acid ethyl ester 
• 37152-74-2 2-bromo-N-(2-morpholin-4-yl-ethyl)-N-phenyl-propionamide 

Relevant articles and documents

Nickel(II)-NΛNΛO Pincer Type Complex-Catalyzed N-alkylation of Amines with Alcohols via the Hydrogen Autotransfer Reaction

A highly sustainable catalytic protocol for the coupling of alcohols and amines for selective monoalkylated amines using Ni(II)-NΛNΛO pincer type complexes through the borrowing hydrogen methodology is described. An array of Ni(II) catalysts (1-3) was synthesized and characterized by various spectral and analytical methods. Furthermore, the distorted square planar geometry of the complexes (1 and 2) was substantiated with single crystal X-ray diffraction study. The inexpensive nickel-based catalytic methodology displays a broad substrate scope for the N-alkylation of aromatic and heteroaromatic amines using a diverse range of primary alcohols with excellent yields up to 97%. The present approach is environmentally benign, which liberates water as the sole byproduct. A short synthesis of drug intermediates such as mepyramine and chloropyramine illustrates the utility of the present protocol.

Potassium iodide catalysed monoalkylation of anilines under microwave irradiation

A potassium iodide catalysed method for the selective N-monoalkylation anilines with alkylhalides and alkyltosylates under microwave irradiation is described. The corresponding N-alkylanilines are obtained in good yields with only minor quantities of dialkylation by-products.

Potential antihistamines with increased receptor specificity.

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