203866-15-3 Usage
Description
N-BOC-4,4-difluoro-L-proline is a synthetically derived amino acid analog characterized by the presence of a difluoromethyl group at the 4,4-position and a tert-butyloxycarbonyl (BOC) protecting group on the nitrogen atom. N-BOC-4,4-difluoro-L-proline exhibits solid-state chemical properties and is utilized in the synthesis of various biologically active molecules.
Uses
Used in Pharmaceutical Research and Development:
N-BOC-4,4-difluoro-L-proline serves as a key reagent in the preparation of pyrrolotriazines, which are compounds of interest in the development of pan-Aurora kinase inhibitors. These inhibitors are crucial for studying the structure-activity relationship and pharmacokinetics of potential anti-tumor agents.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, N-BOC-4,4-difluoro-L-proline is employed as a building block for the synthesis of novel compounds with potential therapeutic applications. Its unique structural features allow for the exploration of new chemical space and the discovery of innovative drug candidates.
Used in Biochemical Studies:
N-BOC-4,4-difluoro-L-proline can be utilized in biochemical studies to investigate the effects of amino acid analogs on protein structure and function. This can provide valuable insights into the role of specific amino acids in biological processes and contribute to the understanding of protein-ligand interactions.
Used in Organic Synthesis:
As a solid organic compound, N-BOC-4,4-difluoro-L-proline can be employed in various organic synthesis processes. Its reactivity and functional groups make it a versatile intermediate for the preparation of complex organic molecules and pharmaceutical intermediates.
Check Digit Verification of cas no
The CAS Registry Mumber 203866-15-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,3,8,6 and 6 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 203866-15:
(8*2)+(7*0)+(6*3)+(5*8)+(4*6)+(3*6)+(2*1)+(1*5)=123
123 % 10 = 3
So 203866-15-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H15F2NO4/c1-9(2,3)17-8(16)13-5-10(11,12)4-6(13)7(14)15/h6H,4-5H2,1-3H3,(H,14,15)/t6-/m0/s1
203866-15-3Relevant articles and documents
ETHANEDIAMINE-HETEROCYCLE DERIVATIVES AS INHIBITORS OF PROTEIN ARGININE METHYLTRANSFERASES
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Paragraph 0738, (2019/09/15)
The present invention relates to ethanediamine-heterocycle compounds that are able to act as inhibitors of PRMTs (protein arginine methyltransferases) for treating cancer and other diseases mediated by PRMTs.
ARYL, HETEROARYL, AND HETEROCYCLIC COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS
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Paragraph 0574, (2017/03/14)
Compounds, methods of use, and processes for making inhibitors of complement Factor D comprising Formula I, or a pharmaceutically acceptable salt or composition thereof wherein R12 or R13 on the A group is an aryl, heteroaryl or heterocycle (R32) are provided. The inhibitors of Factor D described herein reduce the excessive activation of complement.
Bridged Ring compounds As Hepatitis C Virus (HCV) Inhibitors And Pharmaceutical Applications Thereof
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Paragraph 1117; 1124; 1125; 1126; 1127, (2015/03/28)
Provided herein is a compound having Formula (I), or a stereoisomer, a geometric isomer, a tautomer, an N-oxide, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, which can be used for treating HCV infection or a HCV disorder. Also provided herein are pharmaceutical compositions comprising the compounds disclosed herein, which can be used for treating HCV infection or a HCV disorder.
