20394-86-9Relevant articles and documents
Synthesis of alkyl phosphinic acids from silyl phosphonites and alkyl halides
Boyd, E. Andrew,Regan, Andrew C.,James, Keith
, p. 4223 - 4226 (1994)
Mono- and di-substituted phosphinic acids have been synthesised in a one-pot reaction, by the addition of alkyl halides to silyl phosphonites, under mild and flexible conditions.
Rapid and efficient synthesis of unsymmetrical phosphinic acids r′t(o)ohr″
Fougere, Cecile,Guenin, Erwann,Hardouin, Julie,Lecouvey, Marc
experimental part, p. 6048 - 6054 (2010/03/02)
A new synthesis of unsymmetrical phosphinic acids R′P(O)OHR″ has been evaluated, The first P-C bond was formed by base-promoted H-phosphinate alkylation of a protected H-phosphinate, which is easier and safer to handle, A onepot methodology was developed for the second P-C bond formation reaction that: involves the sila-Arbuzov reaction. This methodology was then extended to the synthesis of a dialkylphosphinic acid with an amino functionality.
Efficient synthesis of mono- and diarylphosphinic acids: a microwave-assisted palladium-catalyzed cross-coupling of aryl halides with phosphinate
Kalek, Marcin,Stawinski, Jacek
experimental part, p. 10406 - 10412 (2010/02/27)
A general, efficient method for the microwave-assisted synthesis of mono- and diarylphosphinic acids from anilinium phosphinate and aryl halides, using Pd(0) and Xantphos as a supporting ligand, was developed.
