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204395-49-3

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  • 8-Azaspiro[4.5]decane-7,9-dione,8-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl-1,1,2,2,3,3,4,4-d8]- (9CI)

    Cas No: 204395-49-3

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  • 8-Azaspiro[4.5]decane-7,9-dione,8-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl-1,1,2,2,3,3,4,4-d8]- (9CI)

    Cas No: 204395-49-3

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204395-49-3 Usage

Description

Buspirone (D8), also known as Buspirone-d8 Hydrochloride, is a non-benzodiazepine anxiolytic drug that functions as a 5-hydroxytryptamine (5-HT1) receptor agonist. It is a labeled version of Buspirone, typically used as an internal standard for the quantification of Buspirone by gas chromatography (GC) or liquid chromatography (LC) mass spectrometry. This white solid substance is a valuable tool in the pharmaceutical industry for ensuring accurate measurements and analysis of Buspirone levels.

Uses

Used in Pharmaceutical Industry:
Buspirone (D8) is used as an anxiolytic agent for the treatment of anxiety disorders. It works by selectively binding to 5-HT1 receptors, which helps to alleviate anxiety symptoms without causing the sedative effects or dependence associated with benzodiazepines.
Used in Research and Development:
Buspirone (D8) is used as an internal standard for the quantification of Buspirone by GCor LC-mass spectrometry. This application is crucial for ensuring accurate and precise measurements of Buspirone levels in various samples, such as pharmaceutical formulations, biological fluids, and toxicological studies.
Used in Quality Control and Analysis:
In the pharmaceutical industry, Buspirone (D8) is utilized for quality control and analysis purposes. It helps in verifying the purity, potency, and consistency of Buspirone-containing products, ensuring that they meet the required standards and are safe for consumption.
Used in Toxicological Studies:
Buspirone (D8) can be employed in toxicological studies to investigate the metabolism, distribution, and excretion of Buspirone in the body. This information is vital for understanding the drug's safety profile and potential side effects, as well as for developing effective dosage regimens.

Check Digit Verification of cas no

The CAS Registry Mumber 204395-49-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,4,3,9 and 5 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 204395-49:
(8*2)+(7*0)+(6*4)+(5*3)+(4*9)+(3*5)+(2*4)+(1*9)=123
123 % 10 = 3
So 204395-49-3 is a valid CAS Registry Number.
InChI:InChI=1/C21H31N5O2.ClH/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20;/h5,8-9H,1-4,6-7,10-17H2;1H/i3D2,4D2,10D2,11D2;

204395-49-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 8-[1,1,2,2,3,3,4,4-octadeuterio-4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-8-azaspiro[4.5]decane-7,9-dione,hydrochloride

1.2 Other means of identification

Product number -
Other names Buspirone-d8 Hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:204395-49-3 SDS

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