20518-17-6

Basic information

• Product Name: 1-P-TOLYLPYRAZOLE
• Synonyms: 1-P-TOLYLPYRAZOLE;1-p-tolyl-1H-pyrazole;1-(4-methylphenyl)-1H-Pyrazole;1-(4-methylphenyl)pyrazole
• CAS NO: 20518-17-6
• Molecular Formula: C₁₀H₁₀N₂
• Molecular Weight: 158.2
• Mol File: 20518-17-6.mol
• Article Data: 66

Chemical Properties

• Boiling Point: 251.5°C at 760 mmHg
• Flash Point: 105.9°C
• Appearance: /
• Density: 1.04g/cm³
• Vapor Pressure: 0.0324mmHg at 25°C
• Refractive Index: 1.581
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-P-TOLYLPYRAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-P-TOLYLPYRAZOLE(20518-17-6)
• EPA Substance Registry System: 1-P-TOLYLPYRAZOLE(20518-17-6)

Safety Data

• Hazardous Substances Data: 20518-17-6(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Tetrahedron Letters, 33, p. 659, 1992 DOI: 10.1016/S0040-4039(00)92336-0

InChI:InChI=1/C10H10N2/c1-9-3-5-10(6-4-9)12-8-2-7-11-12/h2-8H,1H3

Upstream product

• 288-13-1 NH-pyrazole 
• 3076-56-0 p-tolyllead triacetate 
• 88254-47-1 (E)-1-(4-tolyl)-2-((E)-3-phenylallylidene)hydrazone 
• 23768-90-3 1,5-di-p-tolyl-1,5-diazapenta-1,3-diene 
• 52913-14-1 O-tosylhydroxylamine 
• 5720-05-8 4-methylphenylboronic acid 
• 106-38-7 para-bromotoluene 
• 624-31-7 4-tolyl iodide 
• 102-52-3 malonaldehydebis(dimethylacetal) 
• 539-44-6 N-4-methylphenylhydrazine 
• 106-49-0 p-toluidine 
• 3483-19-0 3-(4-methylphenyl)sydnone 
• 79-10-7 acrylic acid 
• 106-43-4 para-chlorotoluene 

Downstream Products

• 13910-54-8 N¹-(4-methylphenyl)propane-1,3-diamine 
• 861161-82-2 2-methyl-1-[1-(4-methylphenyl)-1H-pyrazol-5-yl]propan-1-ol 
• 110108-58-2 (5-methyl-2-(1H-pyrazol-1-yl)phenyl)(phenyl)methanone 
• 1190991-80-0 5-methyl-2-(1H-pyrazol-1-yl)benzonitrile 
• 1260140-70-2 4,5-diphenyl-7-methylpyrazolo[1,5-a]quinoline 
• 84401-18-3 1-(2,4-dimethylphenyl)-(1H-pyrazole) 
• 1214622-46-4 5-methyl-2-(1H-pyrazol-1-yl)benzoic acid 
• 1262659-71-1 2-(1H-pyrazol-1-yl)-1,3-benzendicarboxylic acid 1,3-dimethyl ester 
• 1262659-74-4 5-methyl-2-(1H-pyrazol-1-yl)-1,3-benzendicarboxylic acid 1,3-dimethyl ester 
• 1352633-02-3 1-{2-[(E)-2-(n-butoxycarbonyl)ethenyl]-4-methylphenyl}-1H-pyrazole 
• 1352633-04-5 1-{2,6-bis[(E)-2-(n-butoxycarbonyl)ethenyl]-4-methylphenyl}-1H-pyrazole 
• 1417034-40-2 1-[2,6-bis[(1E)-1,2-diphenylethenyl]-4-methylphenyl]pyrazole 
• 337957-59-2 1-(4-methylphenyl)-1H-pyrazole-4-carbaldehyde 
• 1444302-84-4 C₁₀H₉FN₂ 

Relevant articles and documents

N-ARYLATION OF AZOLES AND THEIR BENZO DERIVATIVES BY p-TOLYLLEAD TRIACETATE

The N-arylation of a variety of azoles and their benzo derivatives was achieved by treatment at 90-100 deg c with p-tolyllead triacetate in the presence of copper (II) acetate.

Copper pyrithione (CuPT)-catalyzed/mediated amination and thioarylation of (hetero)aryl halides: A competition

A facile method for the synthesis of N-arylheterocycles and di(hetero)aryl sulfides under mild condition is described. In these transformations, copper pyrithione (CuPT) was used as the copper catalyst for C─N coupling, while served as catalyst and coupled partner for C─S coupling with high yields and broad substrate tolerance. The S-arylation process was also utilized for the construction of valuable bioactive 2-sulfonylpyridine 1-oxide derivatives.

2 - Alkynyl mannose derivative and application thereof

The present invention relates to a 2-alkynyl mannose derivative and an application thereof. The mannose derivative, as well as a pharmaceutically acceptable salt, an isotope and an isomer thereof have the structure represented by general formula I. The de