205255-23-8Relevant articles and documents
Potent and selective inhibitors of platelet-derived growth factor receptor phosphorylation. 1. Synthesis, structure-activity relationship, and biological effects of a new class of quinazoline derivatives
Matsuno, Kenji,Scarborough, Robert M.,Lokker, Nathalie A.,Yu, Jin-Chen,Irie, Junko,Tsukuda, Eiji,Ide, Shin-Ichi,Oda, Shoji,Nomoto, Yuji,Ichimura, Michio,Nakajima, Takao,Tahara, Keiko,Fujiwara, Shigeki,Kase, Hiroshi,Ushiki, Junko,Giese, Neill A.,Pandey, Anjali
, p. 3057 - 3066 (2002)
A new series of 4-[4-(N-substituted carbamoyl)-1-piperazinyl]-6,7-dimethoxyquinazoline derivatives were found to show potent and selective inhibition of platelet-dervied growth factor (PDGF) receptor phosphorylation. In this exploration of the structure-a