20529-20-8

Basic information

• Product Name: 3-[4-(3-chlorophenyl)piperazin-1-yl]propan-1-amine
• Synonyms: 3-[4-(3-chlorophenyl)piperazin-1-yl]propan-1-amine
• CAS NO: 20529-20-8
• Molecular Formula: C₁₃H₂₀ClN₃
• Molecular Weight: 253.771
• Mol File: 20529-20-8.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 396.9±42.0 °C(Predicted)
• Appearance: /
• Density: 1.140±0.06 g/cm3(Predicted)
• PKA: 10.39±0.10(Predicted)
• CAS DataBase Reference: 3-[4-(3-chlorophenyl)piperazin-1-yl]propan-1-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[4-(3-chlorophenyl)piperazin-1-yl]propan-1-amine(20529-20-8)
• EPA Substance Registry System: 3-[4-(3-chlorophenyl)piperazin-1-yl]propan-1-amine(20529-20-8)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 20529-20-8(Hazardous Substances Data)

Upstream product

• 48167-19-7 3-[4-(3-chlorophenyl)-piperazin-1-yl]-propionitrile 
• 6640-24-0 N-(m-chlorophenyl)piperazine 
• 25557-35-1 2-(3-(4-(3-chlorophenyl)-piperazin-1-yl)-propyl)-isoindoline-1,3-dione 

Downstream Products

• 79323-06-1 1-{3-[4-(3-Chloro-phenyl)-piperazin-1-yl]-propyl}-4-(4-methoxy-phenyl)-piperidine-2,6-dione 
• 90619-46-8 3-{3-[4-(3-Chloro-phenyl)-piperazin-1-yl]-propyl}-1,8,8-trimethyl-3-aza-bicyclo[3.2.1]octane-2,4-dione; hydrochloride 
• 3392-10-7 tert-butoxycarbonyl-L-proline N-hydroxysuccinimide ester 
• 184691-36-9 3-({3-[4-(3-Chloro-phenyl)-piperazin-1-yl]-propylcarbamoyl}-methyl)-1-methyl-1H-indole-2-carboxylic acid 
• 184691-73-4 1-Oxo-2,3,4,9-tetrahydro-1H-β-carboline-6-carboxylic acid {3-[4-(3-chloro-phenyl)-piperazin-1-yl]-propyl}-amide 
• 206430-51-5 3-benzhydrylidene-1-{3-[4-(3-chloro-phenyl)-piperazin-1-yl]-propyl}-pyrrolidine-2,5-dione 

Relevant articles and documents

Small-Molecule Inhibition of the UNC119–Cargo Interaction

N-Terminal myristoylation facilitates membrane binding and activity of proteins, in particular of Src family kinases, but the underlying mechanisms are only beginning to be understood. The chaperones UNC119A/B regulate the cellular distribution and signal

Synthesis and biological evaluation of oxazole derivatives as T-type calcium channel blockers

T-type calcium channel is one of therapeutic targets for the treatment of cardiovascular diseases and neuropathic pain. In this study, as a part of our ongoing efforts to develop potent T-type calcium channel blockers, we designed oxazole derivatives subs

POTENTIAL NEUROLEPTICS OF THE ORTHOPRAMIDE SERIES; SYNTHESIS OF N-(3-(TERT.AMINO)PROPYL)-5-SULFAMOYL-2-METHOXYBENZAMIDES

Heating ethyl 5-sulfamoyl-2-methoxybenzoate with a series of twelve 3-(tert.amino)propylamines (IIIa-IIIl) afforded the title compounds IIa-IIl which were transformed to salts and subjected to pharmacological screening as potential neuroleptics of the sulpiride series.Only compounds IId (hydrogen oxalate, VUFB-15 453) and IIg (methanesulfonate, VUFB-15 397) showed indications of the desired psychotropic activity.