20566-48-7

Basic information

• Product Name: 2-[(4-methoxyphenyl)methyl]acrylic acid ethyl ester
• Synonyms: 2-[(4-methoxyphenyl)methyl]acrylic acid ethyl ester
• CAS NO: 20566-48-7
• Molecular Weight: 220.268
• Mol File: 20566-48-7.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2-[(4-methoxyphenyl)methyl]acrylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(4-methoxyphenyl)methyl]acrylic acid ethyl ester(20566-48-7)
• EPA Substance Registry System: 2-[(4-methoxyphenyl)methyl]acrylic acid ethyl ester(20566-48-7)

Safety Data

• Hazardous Substances Data: 20566-48-7(Hazardous Substances Data)

Upstream product

• 35684-37-8 bis(4-methoxyphenyl)ditelluride 
• 17435-72-2 ethyl 2-bromomethyl-2-propenoate 
• 4456-34-2 bis(4-methoxyphenyl)telluride 
• 17435-77-7 ethyl 2-(chloromethyl)acrylate 
• 459-64-3 4-methoxybenzenediazonium tetrafluoroborate 
• 50-00-0 formaldehyd 
• 167547-59-3 2-(4-methoxybenzyl)-3-oxo-3-phenylpropionic acid ethyl ester 
• 2746-25-0 p-Methoxybenzyl bromide 
• 733-53-9 p-methoxyphenyl(phenyl)iodonium tetrafluoroborate 
• 132627-71-5 2-[(4-methylphenylsulfonyl)methyl]propenoic acid ethyl ester 
• 80787-04-8 ethyl 2-(acetoxymethyl)acrylate 
• 33397-21-6 tris(4-methoxyphenyl)bismuth 
• 6335-37-1 2-(4-methoxybenzyl)malonic acid diethyl ester 
• 13139-86-1 4-methoxyphenyl magnesium bromide 

Downstream Products

• 111510-39-5 3-Benzoylthio-2-(p-methoxybenzyl)propionic acid 
• 111510-52-2 3-(benzoylthio)-2-(4-methoxybenzyl)propanoyl chloride 
• 205505-75-5 [(S)-4-(4-Methoxy-benzyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-[2-(2-methoxy-ethoxymethoxy)-phenyl]-methanone 
• 205505-64-2 (S)-4-(4-Methoxy-benzyl)-2,2-dimethyl-[1,3]dioxolane-4-carboxylic acid ethyl ester 
• 205505-81-3 (S)-2-Hydroxy-2-hydroxymethyl-1-(2-hydroxy-phenyl)-3-(4-methoxy-phenyl)-propan-1-one 
• 205505-71-1 (S)-4-(4-Methoxy-benzyl)-2,2-dimethyl-[1,3]dioxolane-4-carbaldehyde 
• 856433-05-1 (2S,5S,8aS)-2-(hydroxymethyl)-2-[(4-methoxyphenyl)methyl]-5-phenyl-1,5,6,8a-tetrahydro-3,7-dioxaindolizin-8(2H)-one 
• 856433-10-8 (2S,4S)-4-(tert-butoxycarbonyl)amino-2-[(4-methoxyphenyl)methyl]-5-oxooxolane-2-carboxylic acid 
• 856433-09-5 (2S,4S)-4-(tert-butoxycarbonyl)amino-2-[(4-methoxyphenyl)methyl]-2-(hydroxymethyl)oxolan-5-one 
• 856433-01-7 2-[(4-methoxyphenyl)methyl]prop-2-en-1-ol 
• 82983-20-8 α-methylene-4-methoxybenzenepropanoic acid 
• 205505-56-2 (S)-2-Hydroxy-2-hydroxymethyl-3-(4-methoxy-phenyl)-propionic acid ethyl ester 

Relevant articles and documents

Enantioselective Enzymatic Reduction of Acrylic Acids

An ene-reductase (ERED 36) with broad substrate specificity was identified, and optimization studies led to the development of an enzymatic protocol for the reduction of α,β-unsaturated acids under mild, aqueous conditions. The substrate scope includes aromatic- A nd aliphatic-substituted acrylic acids, as well as cyclic α,β-substituted acrylic acids, yielding chiral α-substituted acids with exquisite levels of enantioselectivity (>99% ee).

Pd-catalyzed threefold arylation of Baylis-Hillman bromides and acetates with triarylbismuth reagents

Functionalized alkyl 2-benzylacrylates and 2-benzylacrylonitriles were synthesized by means of atom-economic cross-couplings of Baylis-Hillman bromides or acetates with BiAr3 under palladium-catalyzed conditions. These reactions, involving thre

Stereoselective syntheses of 4-hydroxy 4-substituted glutamic acids

The 4-hydroxy 4-substituted glutamic acid moiety is a common substructure of biologically important natural products such as monatin [(2S,4S)-2], lycoperdic acid (3), and dysiherbaine (4). To develop methodology for syntheses of these natural products, cycloadditions of nitrone 5 with 2-substituted 2-propen-1-ols 6 and 2-substituted acrylates 8 were investigated. Reactions of nitrone 5 with alcohols 6 in the presence of MgBr2OEt2 gave cycloadducts 7 in a highly stereoselective manner, whereas noncatalyzed reactions of 5 with acrylates 8 afforded adducts 9. Using the former reaction, syntheses of monatin [(2S,4S)-2], monatin derivative 18, and lycoperdic acid (3) were accomplished. The C4-epimer of monatin [(2S,4R)-2)] was also synthesized by employing the latter cycloaddition.