20600-29-7

Basic information

• Product Name: 1-BROMO-3-(PHENOXYMETHYL)BENZENE
• Synonyms: Benzene, 1-bromo-3-(phenoxymethyl)-
• CAS NO: 20600-29-7
• Molecular Formula: C₁₃H₁₁BrO
• Molecular Weight: 263.1329
• Mol File: 20600-29-7.mol
• Article Data: 4

Chemical Properties

• Melting Point: 38 °C
• Boiling Point: 344.2°C at 760 mmHg
• Flash Point: 141.2°C
• Appearance: /
• Density: 1.382g/cm³
• Vapor Pressure: 0.000133mmHg at 25°C
• Refractive Index: 1.599
• CAS DataBase Reference: 1-BROMO-3-(PHENOXYMETHYL)BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BROMO-3-(PHENOXYMETHYL)BENZENE(20600-29-7)
• EPA Substance Registry System: 1-BROMO-3-(PHENOXYMETHYL)BENZENE(20600-29-7)

Safety Data

• Hazardous Substances Data: 20600-29-7(Hazardous Substances Data)

Usage

Physical State

Clear, colorless liquid

Odor

Faint aromatic

Usage

Manufacturing of pharmaceuticals, herbicides, and other organic chemicals

Structural Feature

Brominated derivative of benzene

Attachment

Phenoxy methyl group attached to the third carbon atom

Role

Intermediate in the synthesis of various compounds

Application

Building blocks in organic chemistry

Reactivity

Ability to undergo various substitution reactions

Value

Production of a wide range of organic compounds

InChI:InChI=1/C13H11BrO/c14-12-6-4-5-11(9-12)10-15-13-7-2-1-3-8-13/h1-9H,10H2

Upstream product

• 456-43-9 1-bromo-3-(fluoromethyl)benzene 
• 139-02-6 sodium phenoxide 
• 932-77-4 3-bromobenzyl chloride 
• 108-95-2 phenol 
• 823-78-9 meta-bromobenzyl bromide 
• 15852-73-0 (3-Bromophenyl)methanol 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 

Downstream Products

• 31719-75-2 3-phenoxymethylbenzoic acid 
• 139-66-2 diphenyl sulfide 
• 13865-48-0 3-methylphenyl phenyl sulfide 
• 946-80-5 (benzyloxy)benzene 
• 211615-07-5 (3-bromobenzyl)(phenyl)sulfane 
• 94306-40-8 Phenyl-(4-phenylmercapto-benzyl)-sulfid 
• 75954-35-7 phenyl p-bromobenzyl sulfide 
• 1423148-49-5 (6-fluoro-4-methyl-3'-(phenoxymethyl)-[1,1'-biphenyl]-3-yl)(2,2,2-trifluoroethyl)sulfane 
• 1423148-50-8 2-fluoro-4-methyl-3'-(phenoxymethyl)-5-((2,2,2-trifluoroethyl)sulfinyl)-1,1'-biphenyl 

Relevant articles and documents

From insertion to multicomponent coupling: Temperature dependent reactions of arynes with aliphatic alcohols

The temperature dependent selectivity switch in the reaction of arynes with aliphatic alcohols in THF has been reported. At -20°C, arynes smoothly insert into the O-H bond of alcohols to form alkyl aryl ethers. Interestingly, at 60°C, a highly selective multicomponent coupling occurs with the solvent THF acting as the nucleophilic trigger affording (4-(alkoxy)butoxy)arenes.

NEW ARYLALKENYLPROPARGYLAMINE DERIVATIVES EXHIBITING NEUROPROTECTIVE ACTION FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES

The invention relates to novel arylalkenylpropargylamine derivatives of general formula (I) or enantiomers or diastereomers thereof or salts, optionally pharmaceutically acceptable salts, or solvates of any of these. The compounds can be used in treating or preventing a disease or condition in a mammal related to monoamine oxidase dysfunction, especially in neurodegenerative diseases, e.g. Parkinson's disease, Alzheimer's disease or Huntington's disease.