206264-60-0

Basic information

• Product Name: (4S,8R,11S)-(-)-11-Benzyl-10,10-diphenyl-9-oxa-1-azatricyclo[6.3.0.0^4,8]undecan-2-one
• Synonyms: (4S,8R,11S)-(-)-11-Benzyl-10,10-diphenyl-9-oxa-1-azatricyclo[6.3.0.0^4,8]undecan-2-one
• CAS NO: 206264-60-0
• Molecular Weight: 409.528
• Mol File: 206264-60-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (4S,8R,11S)-(-)-11-Benzyl-10,10-diphenyl-9-oxa-1-azatricyclo[6.3.0.0^4,8]undecan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4S,8R,11S)-(-)-11-Benzyl-10,10-diphenyl-9-oxa-1-azatricyclo[6.3.0.0^4,8]undecan-2-one(206264-60-0)
• EPA Substance Registry System: (4S,8R,11S)-(-)-11-Benzyl-10,10-diphenyl-9-oxa-1-azatricyclo[6.3.0.0^4,8]undecan-2-one(206264-60-0)

Safety Data

• Hazardous Substances Data: 206264-60-0(Hazardous Substances Data)

Upstream product

• 20826-94-2 ethyl (2-oxocyclopentyl)acetate 
• 79868-78-3 (S)-(-)-2-amino-1,1,3-triphenyl-1-propanol 
• 57728-37-7 DL-2-Amino-1,1,3-triphenyl-1-propanol 

Downstream Products

• 206264-74-6 (2S,1'S,5'S)-2-(2'-azabicyclo<3.3.0>oct-2'-yl)-1,1,3-triphenylpropanol 

Relevant articles and documents

Functionalized 2-azabicyclo[3.3.0]octanes as ligands in the enantioselective catalysis

Enantiopure compounds 4 were prepared by condensation of β- aminoalcohols 2 with ethyl (2-oxocyclopentyl)acetate 1 and subsequent reduction of intermediates 3. Compound 4a was converted to 6 via 5. With compounds 4, 5 or 6 as chiral ligands in the reaction of benzaldehyde with diethylzine an enantiomeric excess between 14 and 84% was achieved.