20651-65-4

Basic information

• Product Name: 1-butyl-4-fluoro-benzene
• Synonyms: 1-butyl-4-fluoro-benzene;p-Fluorobutylbenzene
• CAS NO: 20651-65-4
• Molecular Formula: C₁₀H₁₃F
• Molecular Weight: 152.21
• Mol File: 20651-65-4.mol
• Article Data: 23

Chemical Properties

• Boiling Point: 188℃
• Flash Point: 59℃
• Appearance: /
• Density: 0.954
• Vapor Pressure: 0.863mmHg at 25°C
• Refractive Index: 1.477
• CAS DataBase Reference: 1-butyl-4-fluoro-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-butyl-4-fluoro-benzene(20651-65-4)
• EPA Substance Registry System: 1-butyl-4-fluoro-benzene(20651-65-4)

Safety Data

• Hazardous Substances Data: 20651-65-4(Hazardous Substances Data)

Usage

Physical state at room temperature

Colorless clear liquid

Molecular weight

146.21 g/mol

Uses

Intermediate in chemical synthesis, production of pharmaceuticals, agrochemicals, and other industrial products

Safety precautions

Can be harmful if inhaled, swallowed, or in contact with skin

Handling

Proper personal protective equipment and handling procedures should be observed

InChI:InChI=1/C10H13F/c1-2-3-4-9-5-7-10(11)8-6-9/h5-8H,2-4H2,1H3

Upstream product

• 77153-60-7 1-(4-Butylphenyl)-3,3-(1,5-pentanediyl)triazene 
• 84648-66-8 C₁₂H₁₃FO₄ 
• 84648-70-4 C₁₃H₁₅FO₄ 
• 84648-52-2 C₁₈H₁₆ClFO₄ 
• 134705-05-8 (4-n-Butylphenyl)diazo phenyl sulfide 
• 3874-54-2 4-(4-fluorophenyl)-4-oxo-n-butyl chloride 
• 109-72-8 n-butyllithium 
• 72358-72-6 methanesulfonic acid 4-fluorophenyl ester 
• 215877-38-6 4,5-dimethyl-2-(4-methoxyphenyl)-1,3,2-dioxaborolane 
• 104-13-2 4-Butylaniline 
• 108-86-1 bromobenzene 
• 1215100-19-8 4-n-butylphenyl trifluoromethanesulfonate 
• 66107-29-7 4-methoxyphenyl triflate 
• 41492-05-1 p-bromobutylbenzene 

Downstream Products

• 53179-12-7 Clopimozide 

Relevant articles and documents

Amido PNP pincer complexes of palladium(II) and platinum(II): Synthesis, structure, and reactivity

The synthesis of a series of divalent palladium and platinum complexes containing amido PNP pincer ligands of the type [N(o-C6H4PR2)2]? (R = Ph (1a), iPr (1b)) is reported. Metathetical reactions of [1a–b]PdCl or [1a–b]PtCl with a variety of alkyl Grignard reagents or LiHBEt3 in ethereal or arene solutions generate their corresponding alkyl or hydride complexes [1a]PdR1 (R1 = Me, Et, nBu), [1b]PdR1 (R1 = Me, Et, H), [1a]PtR1 (R1 = Me, Et, nBu, nHexyl, H), and [1b]PtR1 (R1 = Me, H). Although these organometallic complexes are all thermally stable, including those containing β-hydrogen atoms even at elevated temperatures, compounds [1a]PdH and [1b]PtR1 (R1 = Et, nBu, nHexyl) are not isolable due to facile decomposition. The stability and reactivity of these complexes are discussed. The chloro [1a]PdCl is a superior catalyst precursor to [1b]PdCl, [1a]PtCl, and [1b]PtCl in Kumada couplings, affording, for instance, n-butyl arenes nearly quantitatively. The X-ray structures of [1b]PtCl, [1b]PtMe, [1b]PdEt, [1a]PtnBu, [1b]PdH, and [1b]PtH are presented.

Spatially isolated palladium in porous organic polymers by direct knitting for versatile organic transformations

We report here a direct knitting Method for preparation of highly robust, effective while air- and moisture-tolerant, and readily recyclable three-dimensional (3D) porous polymer-Pd network (PPPd) from the widely used Pd(PPh3)4. Electro-beam induced Pd atom crystallization was observed for the first time in organic polymer and revealed the ultrafine dispersion of palladium atoms. Challenging types of Suzuki-Miyaura couplings, reductive coupling of aryl halides and oxidative coupling of arylboronic acid were successively catalyzed by PPPd in aqueous media. Also catalytically selective C–H functionalization reactions were achieved with orders of magnitude more efficient than conventional Pd homogeneous catalysts. The strategy developed here provides a practical method for easy-to-make yet highly efficient heterogeneous catalysis.

A Fluorinated Ligand Enables Room-Temperature and Regioselective Pd-Catalyzed Fluorination of Aryl Triflates and Bromides

A new biaryl monophosphine ligand (AlPhos, L1) allows for the room-temperature Pd-catalyzed fluorination of a variety of activated (hetero)aryl triflates. Furthermore, aryl triflates and bromides that are prone to give mixtures of regioisomeric aryl fluorides with Pd-catalysis can now be converted to the desired aryl fluorides with high regioselectivity. Analysis of the solid-state structures of several Pd(II) complexes, as well as density functional theory (DFT) calculations, shed light on the origin of the enhanced reactivity observed with L1.