20689-54-7

Basic information

• Product Name: 2-Propenoyl chloride, 3-(2-furanyl)-
• Synonyms: 3-furan-2-yl-acryloyl chloride
• CAS NO: 20689-54-7
• Molecular Formula: C7H5ClO2
• Molecular Weight: 156.569
• Mol File: 20689-54-7.mol
• Article Data: 54

Chemical Properties

• CAS DataBase Reference: 2-Propenoyl chloride, 3-(2-furanyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoyl chloride, 3-(2-furanyl)-(20689-54-7)
• EPA Substance Registry System: 2-Propenoyl chloride, 3-(2-furanyl)-(20689-54-7)

Safety Data

• Hazardous Substances Data: 20689-54-7(Hazardous Substances Data)

Upstream product

• 98-01-1 furfural 
• 539-47-9 3-(2-furyl)acrylic acid 
• 539-47-9 3-(fur-2-yl)crotonic acid 

Downstream Products

• 5066-65-9 (E)-3-(furan-2-yl)-1-(4-methoxyphenyl)prop-2-en-1-one 
• 1426293-61-9 (E)-3-(furan-2-yl)-N-(p-tolyl)acrylamide 
• 15341-87-4 N-(4-chloro-phenyl)-3-furan-2-yl-acrylamide 
• 129196-82-3 (E)-3-(furan-2-yl)-N-phenylacrylamide 
• 613686-80-9 diethyl 1-(4-fluorophenyl)-3-(2-furyl)-5-oxopyrrolidine-2,2-dicarboxylate 
• 26163-74-6 4-(3-furan-2-yl-acryloyl)-morpholine 
• 511516-18-0 C₁₅H₁₂O₄ 
• 325693-88-7 C₂₀H₂₂N₂O₂ 
• 1584132-00-2 10-(furan-2-yl)-7-(4-nitrophenylsulfonyl)-7-azaspiro[4.5]decane-1,6,8-trione 
• 2172-16-9 Furyl-acryloyl-imidazol 
• 24008-72-8 N-[3-(2-furyl)acryloyl]-tyrosine methyl ester 
• 65376-39-8 N-[3-(2-furyl)acryloyl]-phenylalanine methyl ester 

Relevant articles and documents

Diastereoselective intermolecular cobalt-catalyzed reductive aldol reactions of α,β-unsaturated amides with ketones

Under cobalt catalysis, diethylzinc mediates the conjugate reduction of αβ-unsaturated amides to produce ethylzinc enolates that react with ketones in situ to produce tertiary alcohol-containing aldol products with up to >19:1 diastereoselectivity.

Design and synthesis novel amide derivatives containing an 1,3,4-oxadiazole moiety as potential antibacterial agents

To find new antibacterial agents, 25 novel amide derivatives containing an 1,3,4-oxadiazole moiety were designed and synthesized, and their antibacterial activity against Xanthomonas oryzae pv. oryzicola (Xoc) and Xanthomonas oryzae pv. oryzae (Xoo) were tested. Interestingly, all target compounds showed excellent antibacterial activities against Xoc and Xoo. The EC50 values of compounds 1–25 against Xoc and Xoo were 1.2–4.0?mg/L and 0.5–2.3?mg/L, respectively, which were significantly superior to those of the thiodiazole copper (95.1 and 89.0?mg/L) and bismerthhibol (73.8 and 68.8?mg/L). For example, the EC50 values of compound 16 against Xoc and Xoo were 1.7 and 0.5?mg/L, respectively. Meanwhile, the curative and protection activity of compound 16 against rice bacterial leaf blight were 42.4% and 42.1%, respectively, which were superior to the control of jiahuangxianjunzuo (34.1% and 32.6%) and thiodiazole copper (33.0% and 27.1%). In addition, compound 16 might suppress the cell growth of Xoo by inhibiting the production of extracellular polysaccharide, the formation of biofilm, changes the cell membrane permeability, and cell surface morphology.

Template-Directed Photochemical Homodimerization and Heterodimerization Reactions of Cinnamic Acids

We developed a general method for the selective photochemical homo- and heterodimerization of cinnamic acid derivatives with the use of commercially available 1,8-dihydroxynaphthalene as a covalent template. A variety of symmetrical and unsymmetrical β-tr

Multicomponent Enantioselective Synthesis of Tetrahydropyridazinones Employing Chiral α,β-Unsaturated Acylammonium Salts

An enantioselective three-component reaction was developed for the synthesis of tetrahydropyridazinones employing chiral α,β-unsaturated acylammonium salts, malonates, and azodicarboxylates. An initial α-amination of a malonate with an azodicarboxylate an