207120-52-3

Basic information

• Product Name: (S)-2-chloro-N-(1-hydroxy-3-phenylpropan-2-yl)acetamide
• Synonyms: (S)-2-chloro-N-(1-hydroxy-3-phenylpropan-2-yl)acetamide
• CAS NO: 207120-52-3
• Molecular Weight: 272.142
• Mol File: 207120-52-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (S)-2-chloro-N-(1-hydroxy-3-phenylpropan-2-yl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-chloro-N-(1-hydroxy-3-phenylpropan-2-yl)acetamide(207120-52-3)
• EPA Substance Registry System: (S)-2-chloro-N-(1-hydroxy-3-phenylpropan-2-yl)acetamide(207120-52-3)

Safety Data

• Hazardous Substances Data: 207120-52-3(Hazardous Substances Data)

Upstream product

• 3182-95-4 L-Phenylalaninol 
• 598-21-0 2-Bromoacetyl bromide 
• 221045-94-9 (S)-(-)-2-amino-3-phenyl-1-(tert-butyldimethylsilyloxy)propane 

Downstream Products

• 101250-48-0 (S)-5-benzylmorpholin-3-one 
• 207120-53-4 3-(2-bromoacetyl)-2,2-dimethyl-4(S)-phenylmethyl-oxazolidine 

Relevant articles and documents

Amine-promoted asymmetric (4+2) annulations for the enantioselective synthesis of tetrahydropyridines: A traceless and recoverable auxiliary strategy

Gone, without a trace: The in situ reaction of 2-(acetoxymethyl)buta-2,3- dienoate and a secondary amine produces a 2-methylene-3-oxobutanoate equivalent that can be used in asymmetric [4+2] annulations with N-tosylimines to provide tetrahydropyridines in

Design and synthesis of novel conformationally restricted HIV protease inhibitors

A set of HIV protease inhibitors represented by compound 2 has previously been described. Structural and conformational analysis of this compound suggested that conformational restriction of the P1/P2 portion of the molecule could lead to a novel set of potent protease inhibitors. Thus, probe compounds 3-7 were designed, synthesized, and found to be potent inhibitors of HIV protease.