20751-75-1 Usage
General Description
4-(Chloroacetyl)-3,4-dihydro-2H-1,4-benzothiazine, also known by its Chemical Abstracts Service number 60028-69-3, is an organic compound with the molecular formula C10H10ClNO2S. It is a benzothiazine derivative that contains a chloroacetyl group, and is used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It has applications in the field of medicinal chemistry, where it is utilized as a building block for the development of new drugs and therapeutic agents. 4-(CHLOROACETYL)-3,4-DIHYDRO-2H-1,4-BENZOTHIAZINE is a white to off-white solid that is sparingly soluble in water, but soluble in organic solvents such as ethanol and dichloromethane. It is important in the study and development of chemical compounds for various applications in the pharmaceutical and agricultural industries.
Check Digit Verification of cas no
The CAS Registry Mumber 20751-75-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,7,5 and 1 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 20751-75:
(7*2)+(6*0)+(5*7)+(4*5)+(3*1)+(2*7)+(1*5)=91
91 % 10 = 1
So 20751-75-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H10ClNOS/c11-7-10(13)12-5-6-14-9-4-2-1-3-8(9)12/h1-4H,5-7H2
20751-75-1Relevant articles and documents
Indoline and piperazine containing derivatives as a novel class of mixed D2/D4 receptor antagonists. Part 1: Identification and structure-activity relationships
Zhao, He,Thurkauf, Andrew,He, Xiaoshu,Hodgetts, Kevin,Zhang, Xiaoyan,Rachwal, Stanislaw,Kover, Renata X.,Hutchison, Alan,Peterson, John,Kieltyka, Andrzej,Brodbeck, Robbin,Primus, Renee,Wasley, Jan W.F.
, p. 3105 - 3109 (2007/10/03)
Optimization of the lead compound 2-[-4-(4-chloro-benzyl)-piperazin-1-yl]-1-(2,3-dihydro-indol-1-yl)-ethanone 1 by systematic structure-activity relation (SAR) studies lead to two potent compounds 2-[-4-(4-chloro-benzyl)-piperazin-1-yl]-1-(2-methy-2,3-dihydro-indol-1-yl)- ethanone 2n and 2-[-4-(4-chloro-benzyl)-piperazin-1-yl]-1-(2-methy-2,3-dihydro-indol-1-yl)- ethanone 7b. Their related synthesis was also reported.
