207725-70-0

Basic information

• Product Name: {(4S,7S)-5-[(5-tert-Butoxycarbonylamino-pentylcarbamoyl)-methyl]-3,6-dioxo-2,5-diaza-tricyclo[6.2.2.0^2,7]dodec-4-yl}-acetic acid methyl ester
• Synonyms: {(4S,7S)-5-[(5-tert-Butoxycarbonylamino-pentylcarbamoyl)-methyl]-3,6-dioxo-2,5-diaza-tricyclo[6.2.2.0^2,7]dodec-4-yl}-acetic acid methyl ester
• CAS NO: 207725-70-0
• Molecular Weight: 508.615
• Mol File: 207725-70-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {(4S,7S)-5-[(5-tert-Butoxycarbonylamino-pentylcarbamoyl)-methyl]-3,6-dioxo-2,5-diaza-tricyclo[6.2.2.0^2,7]dodec-4-yl}-acetic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: {(4S,7S)-5-[(5-tert-Butoxycarbonylamino-pentylcarbamoyl)-methyl]-3,6-dioxo-2,5-diaza-tricyclo[6.2.2.0^2,7]dodec-4-yl}-acetic acid methyl ester(207725-70-0)
• EPA Substance Registry System: {(4S,7S)-5-[(5-tert-Butoxycarbonylamino-pentylcarbamoyl)-methyl]-3,6-dioxo-2,5-diaza-tricyclo[6.2.2.0^2,7]dodec-4-yl}-acetic acid methyl ester(207725-70-0)

Safety Data

• Hazardous Substances Data: 207725-70-0(Hazardous Substances Data)

Upstream product

• 51644-96-3 5-tert-butoxycarbonylamino-1-aminopentane 
• 207725-68-6 (3S,6S)-1,4-diaza-4-carboxymethyl-7,10-ethano-3-methylcarboxymethyl-2,5-dionebicyclo[4.4.0]decane 

Relevant articles and documents

A Constrained Diketopiperazine as a New Scaffold for the Synthesis of Peptidomimetics

As a new scaffold for peptidomimetic synthesis, a highly constrained bifunctional diketopiperazine, 4, has been prepared by smooth N-alkylation with tert-butyl bromoacetate. As a first application, we describe herein the synthesis of new peptidomimetics of the Arg-Gly-Asp (RGD) sequence. The product 30, which shows a selective platelet-aggregation inhibiting activity, can be used as a lead for the preparation of more potent products.