208108-76-3

Basic information

• Product Name: 4-PHENYL-5-(TRIFLUOROMETHYL)THIOPHENE-2-CARBOXYLIC ACID
• Synonyms: BUTTPARK 82\12-88;4-Phenyl-5-(trifluoromethyl)-2-thenoic acid, 5-Carboxy-3-phenyl-2-(trifluoromethyl)thiophene;4-PHENYL-5-(TRIFLUOROMETHYL)THIOPHENE-2-CARBOXYLIC ACID;4-phenyl-5-(trifluoromethyl)-2-thiophenecarboxylic acid
• CAS NO: 208108-76-3
• Molecular Formula: C₁₂H₇F₃O₂S
• Molecular Weight: 272.24
• Mol File: 208108-76-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 130 °C
• Boiling Point: 366.5°C at 760 mmHg
• Flash Point: 175.5°C
• Appearance: /
• Density: 1.431g/cm³
• Vapor Pressure: 5.12E-06mmHg at 25°C
• Refractive Index: 1.555
• CAS DataBase Reference: 4-PHENYL-5-(TRIFLUOROMETHYL)THIOPHENE-2-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-PHENYL-5-(TRIFLUOROMETHYL)THIOPHENE-2-CARBOXYLIC ACID(208108-76-3)
• EPA Substance Registry System: 4-PHENYL-5-(TRIFLUOROMETHYL)THIOPHENE-2-CARBOXYLIC ACID(208108-76-3)

Safety Data

• Hazard Codes: Xi,T
• Statements: 25
• Safety Statements: 45
• Hazardous Substances Data: 208108-76-3(Hazardous Substances Data)

Usage

General Description

4-Phenyl-5-(trifluoromethyl)thiophene-2-carboxylic acid is a chemical compound with a molecular formula of C13H7F3O2S. It is a thiophene derivative with a phenyl and a trifluoromethyl group attached to the 5-position of the thiophene ring. The carboxylic acid functional group is located at the 2-position of the thiophene ring. 4-PHENYL-5-(TRIFLUOROMETHYL)THIOPHENE-2-CARBOXYLIC ACID has potential applications in pharmaceuticals, agrochemicals, and material science due to its unique chemical structure. It may also be used as a building block in the synthesis of more complex organic molecules.

InChI:InChI=1/C12H7F3O2S/c13-12(14,15)10-8(6-9(18-10)11(16)17)7-4-2-1-3-5-7/h1-6H,(H,16,17)

Upstream product

• 167279-18-7 ethyl 5-(trifluoromethyl)-4-phenylthiophene-2-carboxylate 
• 350-92-5 1,1,1-Trifluoro-3-phenylpropan-2-one 
• 119197-24-9 3-chloro-4,4,4-trifluoro-2-phenyl-but-2-enal 

Downstream Products

• 256488-46-7 2-hydroxymethyl-4-phenyl-5-trifluoromethylthiophene 
• 569685-43-4 4-((4-phenyl-5-trifluoromethyl-2-thienyl)methoxy)benzaldehyde 
• 569685-42-3 3-[(4-formyl)phenyl]-5-(4-phenyl-5-trifluoromethyl-2-thienyl)-1,2,4-oxadiazole 
• 569685-50-3 3-[(4-hydroxymethyl)phenyl]-5-(4-phenyl-5-trifluoromethyl-2-thienyl)-1,2,4-oxadiazole 
• 569685-49-0 3-[(4-carbomethoxy)phenyl]-5-(4-phenyl-5-trifluoromethyl-2-thienyl)-1,2,4-oxadiazole 
• 217184-77-5 1-(4-phenyl-5-trifluoromethyl-thiophen-2-yl)-ethanone 
• 1034188-50-5 ethyl 1-[(2-chloro-4-{5-[4-phenyl-5-(trifluoromethyl)-2-thienyl]-1,2,4-oxadiazol-3-yl}phenyl)methyl]-1H-pyrazole-3-carboxylate 
• 1034188-46-9 ethyl 1-[(3-chloro-4-{5-[4-phenyl-5-(trifluoromethyl)-2-thienyl]-1,2,4-oxadiazol-3-yl}phenyl)methyl]-1H-pyrazole-3-carboxylate 
• 1034688-87-3 4-{5-[4-phenyl-5-(trifluoromethyl)-2-thienyl]-1,2,4-oxadiazol-3-yl}-1H-indole 
• 1236202-92-8 (Z)-tert-butyl 1-(4-(N'-(4-phenyl-5-(trifluoromethyl)thiophene-2-carbonyloxy)-carbamimidoyl)benzyl)azetidine-3-carboxylate 
• 1201444-43-0 4-[5-(4-phenyl-5-trifluoromethyl-thiophen-2-yl)-[1,2,4]oxadiazol-3-yl]-pyridine 
• 1201445-66-0 3-(3-methylpyridin-4-yl)-5-(4-phenyl-5-(trifluoromethyl)thiophen-2-yl)-1,2,4-oxadiazole 
• 1034688-73-7 3-(1H-indol-5-yl)-5-(4-phenyl-5-(trifluoromethyl)thiophen-2-yl)-1,2,4-oxadiazole 
• 1201447-81-5 3-(1H-benzo[d]imidazol-5-yl)-5-(4-phenyl-5-(trifluoromethyl)thiophen-2-yl)-1,2,4-oxadiazole 

Relevant articles and documents

NOVEL THIOPHENE DERIVATIVES

The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.

Microbicidal agents based on thiophene-2-carboxylic acid derivatives

PCT No. PCT/EP97/06368 Sec. 371 Date May 26, 1999 Sec. 102(e) Date May 26, 1999 PCT Filed Nov. 14, 1997 PCT Pub. No. WO98/23605 PCT Pub. Date Jun. 4, 1998Novel microbicidal compositions based on thiophene-2-carboxylic acid derivatives, some of which are k