20821-95-8

Basic information

• Product Name: Isoxazole, 4,5-dihydro-5-(4-methylphenyl)-3-phenyl-
• CAS NO: 20821-95-8
• Molecular Formula: C16H15NO
• Molecular Weight: 237.301
• Mol File: 20821-95-8.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: Isoxazole, 4,5-dihydro-5-(4-methylphenyl)-3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Isoxazole, 4,5-dihydro-5-(4-methylphenyl)-3-phenyl-(20821-95-8)
• EPA Substance Registry System: Isoxazole, 4,5-dihydro-5-(4-methylphenyl)-3-phenyl-(20821-95-8)

Safety Data

• Hazardous Substances Data: 20821-95-8(Hazardous Substances Data)

Upstream product

• 1669-50-7 1-phenyl-3-(4-tolyl)propan-1-one 
• 622-97-9 1-ethenyl-4-methylbenzene 
• 98-88-4 benzoyl chloride 
• 100-52-7 benzaldehyde 
• 932-90-1 Benzaldoxime 
• 104-87-0 4-methyl-benzaldehyde 
• 98-86-2 acetophenone 
• 4224-87-7 4-methyl-chalcone 
• 56363-35-0 1-methyl-4-(2-phenylcyclopropyl)benzene 
• 148730-42-1 1-(4-methylphenyl)-2-phenylcyclopropane 
• 22252-14-8 (E)-3-(4-methylphenyl)-1-phenyl-2-propen-1-one 
• 873-67-6 benzonitrile oxide 

Downstream Products

• 16112-19-9 5-(p-methylphenyl)-3-phenyl-2-isoxazole 

Relevant articles and documents

TEMPO-Mediated Selective Synthesis of Isoxazolines, 5-Hydroxy-2-isoxazolines, and Isoxazoles via Aliphatic δ-C(sp3)-H Bond Oxidation of Oximes

Selective synthesis of three different bioactive heterocycles; isoxazolines, 5-hydroxy-2-isoxazolines and isoxazoles from the same starting material using TEMPO (2,2,6,6-Tetramethylpiperidin-1-oxyl) as a radical initiator is reported. Selectivity was achi

Heteroannulation of Alkenes with Enynyl Benziodoxolones and Silver Nitrite Involving CC bond Oxidative Cleavage: Entry to 3-Aryl-?2-isoxazolines

A copper-catalyzed [2 + 2 + 1] heteroannulation of alkenes with enynyl benziodoxolones and AgNO2 involving oxidative cleavage of the CC bond promoted by cooperative Zn(OTf)2, KOAc, and 4 ? MS for producing 3-aryl δ2-isoxazolines is reported. Mechanistic s

Hypoiodite mediated synthesis of isoxazolines from aldoximes and alkenes using catalytic KI and Oxone as the terminal oxidant

Isoxazolines can be efficiently synthesized in good yields via a hypoiodite mediated catalytic oxidative cyclization of aldoximes and alkenes. This reaction involves active iodine species generated in situ from catalytic amounts of KI and Oxone.