20829-97-4

Basic information

• Product Name: 5-NITROISATOIC ANHYDRIDE, TECH.
• Synonyms: 5-NITROISATOIC ANHYDRIDE, TECH.;5-Nitro-2H-3,1-benzoxazine-2,4(1H)-dione;5-Nitro-1H-benzo[d][1,3]oxazine-2,4-dione
• CAS NO: 20829-97-4
• Molecular Formula: C₈H₄N₂O₅
• Molecular Weight: 208.12776
• Product Categories: Anilines, Aromatic Amines and Nitro Compounds
• Mol File: 20829-97-4.mol
• Article Data: 4

Chemical Properties

• Melting Point: 265-266°C (dec.)
• Appearance: /
• Density: 1.623 g/cm³
• Refractive Index: 1.629
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 5-NITROISATOIC ANHYDRIDE, TECH.(CAS DataBase Reference)
• NIST Chemistry Reference: 5-NITROISATOIC ANHYDRIDE, TECH.(20829-97-4)
• EPA Substance Registry System: 5-NITROISATOIC ANHYDRIDE, TECH.(20829-97-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 20829-97-4(Hazardous Substances Data)

Usage

General Description

5-Nitroisatoic anhydride, tech. is a chemical compound that is used in various industrial applications, including as a building block in the synthesis of pharmaceuticals and agrochemicals. It is a nitro-substituted aromatic anhydride that is known for its reactivity and its ability to undergo various chemical reactions. 5-NITROISATOIC ANHYDRIDE, TECH. is also used as a precursor for the synthesis of dyes, pigments, and other organic compounds. It is important to handle 5-nitroisatoic anhydride, tech. with caution, as it may pose health and environmental risks if not used properly.

InChI:InChI=1/C8H4N2O5/c11-7-6-4(9-8(12)15-7)2-1-3-5(6)10(13)14/h1-3H,(H,9,12)

Upstream product

• 872266-38-1 2-azidocarbonyl-6-nitro-benzoic acid 
• 675575-44-7 2-ethoxycarbonylamino-6-nitro-benzoic acid 
• 603-83-8 3-nitro-o-tolylamine 
• 381670-28-6 (2-methyl-3-nitro-phenyl)-carbamic acid ethyl ester 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 50573-74-5 6-nitroanthranilic acid 
• 603-12-3 2,6-dinitrobenzoic acid 

Downstream Products

• 675575-44-7 2-ethoxycarbonylamino-6-nitro-benzoic acid 
• 99-09-2 3-nitro-aniline 
• 50573-74-5 6-nitroanthranilic acid 
• 185305-73-1 (2-Amino-6-nitro-phenyl)-pyrrolidin-1-yl-methanone 
• 185305-71-9 (2-Amino-6-nitro-phenyl)-piperidin-1-yl-methanone 
• 185305-66-2 (2-Allyl-pyrrolidin-1-yl)-(2-amino-phenyl)-methanone 
• 185305-27-5 (2-Allyl-piperidin-1-yl)-(2-amino-phenyl)-methanone 
• 185305-62-8 (2-Amino-phenyl)-(2-propyl-pyrrolidin-1-yl)-methanone 
• 185305-25-3 (2-Amino-phenyl)-(2-propyl-piperidin-1-yl)-methanone 
• 185305-76-4 (2-Methoxy-pyrrolidin-1-yl)-(2-nitro-phenyl)-methanone 
• 185305-80-0 (2-Allyl-pyrrolidin-1-yl)-(2-nitro-phenyl)-methanone 
• 185305-78-6 (2-Allyl-piperidin-1-yl)-(2-nitro-phenyl)-methanone 
• 185305-74-2 (2-Methoxy-piperidin-1-yl)-(2-nitro-phenyl)-methanone 

Relevant articles and documents

Synthesis and nematicidal activities of 1,2,3-benzotriazin-4-one containing 4,5-dihydrothiazole-2-thiol derivatives against Meloidogyne incognita

A series of novel 1,2,3-benzotriazin-4-one derivatives containing 4,5-dihydrothiazole-2-thiol were synthesized and characterized by 1H NMR, 13C NMR, 19F NMR and HRMS. The bioassay results showed that compounds 3-(3-((4,5-dihydrothiazol-2-yl)thio)propyl)-7-methoxybenzo[d][1–3]triazin-4(3H)-one, 3-(3-((4,5-dihydrothiazol-2-yl)thio)propyl)-6-nitrobenzo[d][1–3]triazin-4(3H)-one, 7-chloro-3-(3-((4,5-dihydrothiazol-2-yl)thio)propyl)benzo[d][1–3]triazin-4(3H)-one exhibited good control efficacy against the cucumber root-knot nematode disease caused by Meloidogyne incognita at the concentration of 10.0 mg L?1 in vivo. Compound 7-chloro-3-(3-((4,5-dihydrothiazol-2-yl)thio)propyl)benzo[d][1–3]triazin-4(3H)-one showed excellent nematicidal activity with inhibition 68.3% at a concentration of 1.0 mg L?1. It suggested that the structure of 1,2,3-benzotriazin-4-one containing 4,5-dihydro-thiazole-2-thiol could be optimized further.

4,4-DISUBSTITUTED PIPERIDINE DERIVATIVES HAVING CCR3 ANTAGONISM

The invention provides low molecular compounds having activity which inhibits binding of CCR3 ligands to CCR3 on target cells, i.e. CCR3 antagonists. The invention also provides 4,4-(disubstituted)piperidine derivatives represented by formula (I) below, pharmaceutically acceptable acid adducts thereof, or pharmaceutically acceptable C1-C6 alkyl adducts thereof, as well as pharmaceutical compositions comprising them as effective ingredients, which are useful for treatment or prevention of diseases associated with CCR3, such as asthma and allergic rhinitis.