20857-21-0 Usage
General Description
2-Pyridinecarboxaldehyde, 6-acetyl- (9CI) is a chemical compound with the molecular formula C8H7NO. It is a derivative of pyridinecarboxaldehyde, and its structure includes a pyridine ring with an acetyl group attached to the sixth carbon atom. 2-Pyridinecarboxaldehyde, 6-acetyl- (9CI) is commonly used in organic synthesis as a key intermediate in the production of various pharmaceuticals, agrochemicals, and other organic compounds. Its acetyl group makes it an important building block for the synthesis of various heterocyclic compounds and can be used in the development of new drugs and therapeutic agents. Additionally, it is used as a flavoring and fragrance ingredient in the food and cosmetic industries, as well as a reagent in chemical research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 20857-21-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,8,5 and 7 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 20857-21:
(7*2)+(6*0)+(5*8)+(4*5)+(3*7)+(2*2)+(1*1)=100
100 % 10 = 0
So 20857-21-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H7NO2/c1-6(11)8-4-2-3-7(5-10)9-8/h2-5H,1H3
20857-21-0Relevant articles and documents
Preparation and antioxidant activity of α-pyridoin and its derivatives
Hatanaka, Masashi,Takahashi, Kyoko,Nakamura, Shigeo,Mashino, Tadahiko
, p. 6763 - 6770 (2007/10/03)
Focusing on α-pyridoin (1, 1,2-di(2-pyridyl)-1,2-ethenediol) as the lead compound of the novel antioxidative enediol, we synthesized 5,5′- or 6,6′-bis-substituted derivatives of 1 from disubstituted pyridines. The antioxidant activity of 1 and its synthetic derivatives 2-7 was evaluated by DPPH (1,1-diphenyl-2-picrylhydrazyl radical) scavenging assay and inhibition of lipid peroxidation. In the DPPH assay, 1 exhibited an activity stronger than that of ascorbic acid, and 5,5′-dimethyl-(5) or 5,5′-dimethoxy- substituted derivatives (6) exhibited more potent activity than 1. The DPPH scavenging activities of α-pyridoins were correlated with their oxidation potential and thus the electron density of enediol. 5 and 6 effectively inhibited lipid peroxidation in the rat liver microsome/tert-butyl hydroperoxide system. Therefore, 5 and 6 serve as good candidates for a pharmacologically useful enediol antioxidant.
