20857-47-0

Basic information

• Product Name: 3,5-BIS(TRIFLUOROMETHYL)PYRIDINE
• Synonyms: 3,5-DI(TRIFLUOROMETHYL)PYRIDINE;3,5-BIS(TRIFLUOROMETHYL)PYRIDINE
• CAS NO: 20857-47-0
• Molecular Formula: C₇H₃F₆N
• Molecular Weight: 215.1
• EINECS: -0
• Product Categories: Pyridine;Building Blocks;C7 to C8;Chemical Synthesis;Heterocyclic Building Blocks;Pyridines
• Mol File: 20857-47-0.mol
• Article Data: 1

Chemical Properties

• Melting Point: 34-38 °C
• Boiling Point: 117-118°C
• Flash Point: 112 °F
• Appearance: /
• Density: 1.437 g/cm³
• Vapor Pressure: 16.5mmHg at 25°C
• Refractive Index: 1.375
• BRN: 1684576
• CAS DataBase Reference: 3,5-BIS(TRIFLUOROMETHYL)PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-BIS(TRIFLUOROMETHYL)PYRIDINE(20857-47-0)
• EPA Substance Registry System: 3,5-BIS(TRIFLUOROMETHYL)PYRIDINE(20857-47-0)

Safety Data

• Hazard Codes: F,T,Xi
• Statements: 11-25-37/38-41
• Safety Statements: 26-39-45
• RIDADR: UN 2926 4.1/PG 3
• WGK Germany: 3
• HazardClass: IRRITANT, TOXIC
• PackingGroup: II
• Hazardous Substances Data: 20857-47-0(Hazardous Substances Data)

Usage

General Description

3,5-Bis(trifluoromethyl)pyridine is a chemical compound that falls into the category of organofluorines. The trifluoromethyl groups present in its molecular structure make it a fluorinated compound. This particular chemical is often used in research and industry due to its distinct properties. Its molecular formula is C7H3F6N and it is categorized under aromatic halides, specifically pyridines. It is generally available as a liquid and is colorless. Although its properties can be exploited in various chemical reactions, handling it requires caution due to potential health risks if it is improperly handled or inhaled.

InChI:InChI=1/C7H3F6N/c8-6(9,10)4-1-5(3-14-2-4)7(11,12)13/h1-3H

Upstream product

• 110-86-1 pyridine 
• 2314-97-8 iodotrifluoromethane 

Relevant articles and documents

Lewis Acidic Boranes, Lewis Bases, and Equilibrium Constants: A Reliable Scaffold for a Quantitative Lewis Acidity/Basicity Scale

A quantitative Lewis acidity/basicity scale toward boron-centered Lewis acids has been developed based on a set of 90 experimental equilibrium constants for the reactions of triarylboranes with various O-, N-, S-, and P-centered Lewis bases in dichloromethane at 20 °C. Analysis with the linear free energy relationship log KB=LAB+LBB allows equilibrium constants, KB, to be calculated for any type of borane/Lewis base combination through the sum of two descriptors, one for Lewis acidity (LAB) and one for Lewis basicity (LBB). The resulting Lewis acidity/basicity scale is independent of fixed reference acids/bases and valid for various types of trivalent boron-centered Lewis acids. It is demonstrated that the newly developed Lewis acidity/basicity scale is easily extendable through linear relationships with quantum-chemically calculated or common physical–organic descriptors and known thermodynamic data (ΔH (Formula presented.)). Furthermore, this experimental platform can be utilized for the rational development of borane-catalyzed reactions.