2089-31-8

Basic information

• Product Name: Ethanone, 1-[4-(1-methylethyl)phenyl]-, oxime
• CAS NO: 2089-31-8
• Molecular Formula: C11H15NO
• Molecular Weight: 177.246
• Mol File: 2089-31-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-[4-(1-methylethyl)phenyl]-, oxime(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[4-(1-methylethyl)phenyl]-, oxime(2089-31-8)
• EPA Substance Registry System: Ethanone, 1-[4-(1-methylethyl)phenyl]-, oxime(2089-31-8)

Safety Data

• Hazardous Substances Data: 2089-31-8(Hazardous Substances Data)

Usage

General Description

Ethanone, 1-[4-(1-methylethyl)phenyl]-, oxime is a chemical compound with the molecular formula C11H15NO. It is also known as 4’-Isopropylacetophenone oxime and is commonly used as a pharmaceutical intermediate. It is a white to pale yellow crystalline solid that is soluble in organic solvents. Ethanone, 1-[4-(1-methylethyl)phenyl]-, oxime has applications in various fields such as medicine, agriculture, and research. Its oxime functional group allows it to participate in various chemical reactions and is commonly used as a building block for the synthesis of other compounds. Additionally, it may be used as a ligand in coordination chemistry or as a reagent in organic synthesis.

Upstream product

• 645-13-6 4-isopropylacetophenone 
• 98-82-8 Isopropylbenzene 

Downstream Products

• 88054-93-7 1-Vinyl-2-(p-isopropenylphenyl)pyrrole 
• 5702-74-9 N-(4-iso-propylphenyl)acetamide 
• 134899-65-3 N-{1-[(E)-4-Isopropyl-phenylimino]-ethyl}-3-nitro-N-(4-nitro-phenyl)-benzenesulfonamide 
• 645-13-6 4-isopropylacetophenone 
• 93971-52-9 2-(4-isopropylphenyl)-1H-pyrrole 

Relevant articles and documents

Rhodium-Catalyzed C?H Activation/Annulation Cascade of Aryl Oximes and Propargyl Alcohols to Isoquinoline N-Oxides

A β-hydroxy elimination instead of common oxidization to carbonyl group in secondary propargyl alcohols was successfully developed to form 2-benzyl substituted isoquinoline N-oxides by a Rhodium-catalyzed C?H activation and annulation cascade, in which moderate to excellent yields (up to 92%) could be obtained under mild reaction conditions, along with good regioselectivity, broad generality and applicability. (Figure presented.).

SO2F2-Activated Efficient Beckmann Rearrangement of Ketoximes for Accessing Amides and Lactams

A novel, mild and practical protocol for the efficient activation of the Beckmann rearrangement utilizing the readily available and economical sulfuryl fluoride (SO2F2 gas) has been developed. The substrate scope of the operationally simple methodology has been demonstrated by 37 examples with good to nearly quantitative isolated yields (over 90 % yield in most cases) in a short time, including B(OH)2, COOH, NH2, and OH substituted substrates. A tentative mechanism was proposed involving formation and elimination of key intermediate, sulfonyl ester.

Rh(III)- and Zn(II)-Catalyzed Synthesis of Quinazoline N-Oxides via C-H Amidation-Cyclization of Oximes

Quinazoline N-oxides have been prepared from simple ketoximes and 1,4,2-dioxazol-5-ones via Rh(III)-catalyzed C-H activation-amidation of the ketoximes and subsequent Zn(II)-catalyzed cyclization. The substrate scope and functional group compatibility were examined. The reaction features relay catalysis by Rh(III) and Zn(II).