20901-53-5

Basic information

• Product Name: methyl 2,3-dihydro-2-oxo-1H-imidazole-4-carboxylate
• Synonyms: methyl 2,3-dihydro-2-oxo-1H-imidazole-4-carboxylate;2,3-Dihydro-2-oxo-1H-imidazole-4-carboxylic acid methyl ester;Einecs 244-106-7;Methyl 2-Oxo-2,3-dihydro-1H-iMidazole-4-carboxylate;1H-IMidazole-4-carboxylic acid, 2,3-dihydro-2-oxo-, Methyl ester;Methyl 2-oxo-1,3-dihydroiMidazole-4-carboxylate
• CAS NO: 20901-53-5
• Molecular Formula: C₅H₆N₂O₃
• Molecular Weight: 142.11274
• EINECS: 244-106-7
• Mol File: 20901-53-5.mol
• Article Data: 3

Chemical Properties

• Melting Point: 280 °C
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.338g/cm³
• Refractive Index: 1.499
• Storage Temp.: 2-8°C
• PKA: 10.54±0.70(Predicted)
• CAS DataBase Reference: methyl 2,3-dihydro-2-oxo-1H-imidazole-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2,3-dihydro-2-oxo-1H-imidazole-4-carboxylate(20901-53-5)
• EPA Substance Registry System: methyl 2,3-dihydro-2-oxo-1H-imidazole-4-carboxylate(20901-53-5)

Safety Data

• Hazardous Substances Data: 20901-53-5(Hazardous Substances Data)

Usage

General Description

Methyl 2,3-dihydro-2-oxo-1H-imidazole-4-carboxylate is a chemical compound with the molecular formula C6H7N3O3. It is a derivative of imidazole and is commonly used in pharmaceutical research as a precursor for the synthesis of various bioactive compounds, including potential drug candidates. methyl 2,3-dihydro-2-oxo-1H-imidazole-4-carboxylate has been studied for its potential antifungal and antibacterial properties, as well as its ability to inhibit certain enzymes and receptors in the human body. Its unique structure and reactivity make it a valuable building block for the design and development of new therapeutic agents. Additionally, it also finds applications in the field of organic synthesis and medicinal chemistry.

InChI:InChI=1/C5H6N2O3/c1-10-4(8)3-2-6-5(9)7-3/h2H,1H3,(H2,6,7,9)

Upstream product

• 157001-86-0 methyl (4S)-2-oxoimidazolidine-4-carboxylate 
• 67-56-1 methanol 
• 39828-47-2 2-oxo-4-imidazoline-4-carboxylic acid 

Downstream Products

• 852615-13-5 1-(p-toluenesulfonyl)-4-(methoxycarbonyl)-2,3-dihydro-1H-imidazol-2-one 
• 852615-18-0 2-oxo-1-[2-(toluene-4-sulfonyl)-vinyl]-2,3-dihydro-1H-imidazole-4-carboxylic acid methyl ester 
• 896141-17-6 1,3-bis(benzyloxymethyl)-4-(methoxycarbonyl)-2,3-dihydro-1H-imidazol-2-one 
• 852615-22-6 2-oxo-1-[2-(toluene-4-sulfonyl)-ethyl]-2,3-dihydro-1H-imidazole-4-carboxylic acid methyl ester 
• 852615-14-6 1-(p-toluenesulfonyl)-3-(3,4-dimethoxybenzyl)-4-(methoxycarbonyl)-2,3-dihydro-1H-imidazol-2-one 
• 852615-23-7 3-(3,4-dimethoxybenzyl)-2-oxo-1-[2-(toluene-4-sulfonyl)-ethyl]-2,3-dihydro-1H-imidazole-4-carboxylic acid methyl ester 
• 896141-27-8 1-tert-butoxycarbonyl-3-(4-methoxybenzyl)-4-(methoxycarbonyl)-2,3-dihydro-1H-imidazol-2-one 
• 896141-29-0 1-(p-toluenesulfonyl)-3-(4-methoxybenzyl)-4-(methoxycarbonyl)-2,3-dihydro-1H-imidazol-2-one 

Relevant articles and documents

Diastereoselective Cycloaddition of Allyltrialkylsilanes to Intermediate N-Acyliminoesters Obtained from Methyl 4-Methoxy-2-Imidazolidinone- and 2-Oxazolidinone-4-carboxylates

The amidoalkylation reaction of methyl 4-methoxy-2-imidazolidinone-4-carboxylates or methyl 4-methoxy-2-oxazolidinone-4-carboxylates using allylsilanes as nucleophiles in the presence of TiCl4 affords three carbon ring annulation products 5 and 9 via a cycloaddition.Besides that, the simple methoxy group substitution product is formed.The ring annulation occurs with practically total diastereoselectivity so that all substituents are located on the β-side of the bicyclic product.

Nucleosides. LII. Transformations of pyrimidine nucleosides in alkaline media. I. The conversion of 5-halogenoarabinosyluracils into imidazoline nucleosides.

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