209901-49-5Relevant articles and documents
Design, synthesis and biological evaluation of pentacyclic triterpene derivatives: Optimization of anti-Abl kinase activity
Ciftci, Halil I.,Radwan, Mohamed O.,Ozturk, Safiye E.,Gokce Ulusoy,Sozer, Ece,Ellakwa, Doha E.,Ocak, Zeynep,Can, Mustafa,Ali, Taha F.S.,Abd-Alla, Howaida I.,Yayli, Nurettin,Tateishi, Hiroshi,Otsuka, Masami,Fujita, Mikako
, (2019)
Imatinib, an Abelson (ABL) tyrosine kinase inhibitor, is a lead molecular-targeted drug against chronic myelogenous leukemia (CML). To overcome its resistance and adverse effects, new inhibitors of ABL kinase are needed. Our previous study showed that the