2104-05-4

Basic information

• Product Name: 2(3H)-Thiazolethione, 4-(4-methoxyphenyl)-
• CAS NO: 2104-05-4
• Molecular Formula: C10H9NOS2
• Molecular Weight: 223.32
• Mol File: 2104-05-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2(3H)-Thiazolethione, 4-(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(3H)-Thiazolethione, 4-(4-methoxyphenyl)-(2104-05-4)
• EPA Substance Registry System: 2(3H)-Thiazolethione, 4-(4-methoxyphenyl)-(2104-05-4)

Safety Data

• Hazardous Substances Data: 2104-05-4(Hazardous Substances Data)

Usage

Structure

Thiazole derivative with a methylthio group and a 4-methoxyphenyl group attached to the thiazole ring

Pharmaceutical properties

Potential anti-inflammatory and analgesic effects

Possible applications

Development of new drugs for the treatment of various diseases

Safety precautions

Handle with caution and follow safety and handling guidelines in laboratory or industrial settings.

Upstream product

• 513-74-6 ammonium dithiocarbamate 
• 2632-13-5 2-Bromo-4'-methoxyacetophenone 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 41068-36-4 2-chloro-4-methoxyacetophenone 
• 93435-57-5 α-tosyloxy-p-methoxyacetophenone 
• 507-09-5 thioacetic acid 
• 6097-26-3 p-methoxyphenacyl thiocyanate 

Downstream Products

• 69426-52-4 2-butylsulfanyl-4-(4-methoxy-phenyl)-thiazole 
• 22997-27-9 4-[4-(4-methoxy-phenyl)-thiazol-2-ylsulfanyl]-butan-2-one 
• 130459-58-4 [4-(4-Methoxy-phenyl)-thiazol-2-ylsulfanyl]-acetonitrile 
• 130459-66-4 8-Methoxy-3-[4-(4-methoxy-phenyl)-thiazol-2-ylsulfanyl]-chromen-2-ylideneamine 
• 130459-62-0 3-[4-(4-Methoxy-phenyl)-thiazol-2-ylsulfanyl]-chromen-2-ylideneamine 
• 116626-09-6 4-(4''-methoxyphenyl)-2-(5'-methylmercapto-1',3',4'-oxadiazol-5'-ylmethylmercapto)thiazole 
• 116626-05-2 4-(4''-methoxyphenyl)-2-(5'-mercapto-1',3',4'-oxadiazol-5'-ylmethylmercapto)thiazole 
• 112779-63-2 [4-(4-Methoxy-phenyl)-thiazol-2-ylsulfanyl]-acetic acid [1-(2-hydroxy-3-methoxy-phenyl)-meth-(E)-ylidene]-hydrazide 
• 112779-62-1 [4-(4-Methoxy-phenyl)-thiazol-2-ylsulfanyl]-acetic acid [1-(2-hydroxy-phenyl)-meth-(E)-ylidene]-hydrazide 
• 112779-68-7 <4-(4'-methoxyphenyl)thiazol-2-ylthio>acetic acid hydrazide 
• 112779-57-4 3-<4'-(4''-methoxyphenyl)thiazol-2'-ylthio>-8-methoxy-2H-1-benzopyran-2-one 
• 112779-56-3 3-<4'-(4''-methoxyphenyl)thiazol-2'-ylthio>-2H-1-benzopyran-2-one 
• 2575-01-1 Queen Substance of Honey-bee 
• 81886-43-3 (Z)-9-Oxo-dec-3-enoic acid 

Relevant articles and documents

Synthesis of novel azabicyclo derivatives containing a thiazole moiety and their biological activity against pine-wood nematodes

To explore a new skeleton with nematicidal activity, a series of novel azabicyclo derivatives containing a thiazole moiety were designed, synthesized and evaluated for their nematicidal activities. The bioassay results against pine-wood nematodes (Bursaphelenchus xylophilus) showed that most of the title compounds displayed nematicidal activity at a concentration of 40 mg/L. Especially, the title compounds2-((8-methyl-8-azabicyclo[3.2.1]octan-3-yl)oxy)-4-(4-chlorophenyl)thiazole (7e), 2-((8-methyl-8-azabicyclo[3.2.1]octan-3-yl)thio)-4-phenylthiazole (10a) and 2-((8-methyl-8-azabicyclo [3.2.1]octan-3-yl)thio)-4-(4-chlorophenyl)thiazole (10e) exhibited more than 90% mortality against Bursaphelenchus xylophilus.

2-[3H-THIAZOL-2-YLIDINEMETHYL]PYRIDINES AND RELATED COMPOUNDS AND THEIR USE

The present invention pertains to certain 2-[3H-thiazol-2-ylidinemethyl]pyridine compounds and analogs thereof, which, inter alia, inhibit cell proliferation, treat cancer, etc., and more specifically to compounds of the following formula, wherein RA1, RA2, RA3, RA4, RB1, RB2, RNA, RNB, and X? are as defined herein: The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit cell proliferation, and in the treatment of proliferative conditions such as cancer, etc.

AN UNUSUAL OBSERVATION IN THE SYNTHESIS OF THIOZOLES

Dibromoacetyl benzene derivatives on condensation with thiourea give 2-amino-4-arylthiazoles instead of the expected 2-amino-4-aryl-5-bromothiazoles.Attempts have been made to find the reaction pathway.