21071-28-3

Basic information

• Product Name: N,N'-DIHEXYLTHIOUREA
• Synonyms: TIMTEC-BB SBB007700;N,N'-DIHEXYLTHIOUREA;N,N'-DI-N-HEXYLTHIOUREA;-Di-n-hexylthiourea;1,3-(dihexyl)thiourea;1,3-DIHEXYL-2-thiourea;N,N- Di-n-hexylthirouea
• CAS NO: 21071-28-3
• Molecular Formula: C₁₃H₂₈N₂S
• Molecular Weight: 244.44
• EINECS: 244-191-0
• Mol File: 21071-28-3.mol
• Article Data: 6

Chemical Properties

• Melting Point: 39-41°C
• Boiling Point: 322.1 °C at 760 mmHg
• Flash Point: 148.6 °C
• Appearance: /
• Density: 0.919g/cm³
• PKA: 14.36±0.70(Predicted)
• CAS DataBase Reference: N,N'-DIHEXYLTHIOUREA(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-DIHEXYLTHIOUREA(21071-28-3)
• EPA Substance Registry System: N,N'-DIHEXYLTHIOUREA(21071-28-3)

Safety Data

• Statements: 22
• Safety Statements: 22-36/37
• Hazardous Substances Data: 21071-28-3(Hazardous Substances Data)

Usage

General Description

N,N'-DIHEXYLTHIOUREA is an organic compound with the molecular formula C14H30N2S. It is a thioamide derivative, and its structure consists of a thiourea group attached to two hexyl chains. This chemical is often used as a chelating agent in various industrial processes, particularly in the mining and metal extraction industries. Its ability to form stable complexes with metal ions makes it valuable for applications such as metal recovery, separation, and purification. N,N'-DIHEXYLTHIOUREA is also used in some pesticide formulations and as a corrosion inhibitor in lubricants and metalworking fluids. Additionally, it has potential applications in the medical and pharmaceutical fields, although its use in these areas is limited. Due to its low solubility in water and moderate toxicity, proper handling and storage of N,N'-DIHEXYLTHIOUREA are necessary to minimize potential risks to human health and the environment.

Upstream product

• 111-26-2 hexan-1-amine 
• 4404-45-9 n-hexyl isothiocyanate 
• 110-91-8 morpholine 
• 75-15-0 carbon disulfide 
• 64-04-0 phenethylamine 
• 2450-71-7 Propargylamine 

Downstream Products

• 59814-56-1 4-(4-Chloro-3-sulfamoylphenyl)-3-n-hexyl-2-n-hexylimino-1,3-thiazolidine-4-ol-hydrochloride 

Relevant articles and documents

Photoinduced and Thermal Isomerization Processes for Bis-Oxonols: Rotor Volume, Stereochemical and Viscosity Effects

Four bis-oxonols have been synthesized which possess different alkyl substituents appended to the thiobarbiturate subunit.The nature of the alkyl substituent affects the photophysical properties of the dye in solution since it modulates the rate of rotation of the thiobarbiturate subunit around one of the double bonds in the connecting trimethine bridge.Rates of light-induced (trans to cis) and thermal (cis to trans) isomerization processes have been measured for one of the dyes in protic (i.e. alkanols) and aprotic solvents at various temperatures.These rates, together with activation energies derived from Arrhenius plots, are discussed in terms of the hydrogen bonding and stereochemical properties of the solvent.The thermal step is very sensitive to the stereochemistry of the solvent while the light-induced process is controlled mostly by the size of the rotor and the solvent viscosity.The overall effects may be explained, at least in a qualitative sense, in terms of the medium-enhanced barrier model.

A highly efficient one-pot method for the synthesis of thioureas and 2-imino-4-thiazolidinones under microwave conditions

A one-pot synthesis of symmetrical and unsymmetrical substituted thioureas and 2-imino-4-thiazolidinones from simple starting materials under microwave irradiation and solventless conditions without base additives is presented. Various di- and trisubstituted thioureas are obtained in good yields in a few minutes. The sequential, three-component, one-pot synthesis of 2-imino-4-thiazolidinone derivatives is also studied, with satisfactory results obtained.

A concise synthesis of substituted thiourea derivatives in aqueous medium

(Figure Presented) An efficient method for the synthesis of symmetrical and unsymmetrical substituted thiourea derivatives by means of simple condensation between available building blocks such as amines and carbon disulfide in aqueous medium is presented. This protocol works smoothly with aliphatic primary amines to afford various di- and trisubstituted thiourea derivatives. The present method is also useful in synthesizing various substituted 2-mercapto imidazole heterocycles. This method proceeds through a xanthate (amino dithiol deivative) intermediate, unlike isothiocyanate as in an earlier known method.