210910-25-1Relevant articles and documents
Carvacrol codrugs: A new approach in the antimicrobial plan
Cacciatore, Ivana,Di Giulio, Mara,Fornasari, Erika,Di Stefano, Antonio,Cerasa, Laura Serafina,Marinelli, Lisa,Turkez, Hasan,Di Campli, Emanuela,Di Bartolomeo, Soraya,Robuffo, Iole,Cellini, Luigina
, (2015)
Objective: The increasing prevalence of antibiotic-resistant bacterial infections led to identify alternative strategies for a novel therapeutic approach. In this study, we synthesized ten carvacrol codrugs - obtained linking the carvacrol hydroxyl group
L-Methionine related 1-amino acids by acylase cleavage of their corresponding N-acetyl-DL-derivatives
Bommarius, Andreas S.,Drauz, Karlheinz,Guenther, Kurt,Knaup, Guenter,Schwarm, Michael
, p. 3197 - 3200 (2007/10/03)
Acylase I from Aspergillus oryzae is an even more useful enzyme than suggested so far. Besides standard amino acids such as L-Met, L-Val and L-Phe, a number of additional sulfur- and selenium-containing amino acids can be obtained at useful reaction rates and in very high enantiomeric purity by kinetic resolution of the respective N-acetyl-DL-amino acids.
