211188-29-3Relevant articles and documents
Stereoselective synthesis of α-substituted serines from protected erythrulose oximes
Carda,Murga,Rodriguez,Gonzalez,Castillo,Marco
, p. 1703 - 1712 (2007/10/03)
The additions of organolithium reagents to the C=N bond of several chiral oxime ethers derived from erythrulose afforded protected amino polyols with high diastereoselectivity. Four of the latter compounds have been convened into the α,α-disubstituted α-amino acids (R)-2-(-)-methylserine, (S)-2-(+)-methylserine, (R)-(+)-2-phenylserine and (R)-(-)-2-n-butylserine.