211557-37-8

Basic information

• Product Name: Bis[di(2-pyridyl)methyl]amine
• Synonyms: Bis[di(2-pyridyl)methyl]amine
• CAS NO: 211557-37-8
• Molecular Weight: 353.426
• Mol File: 211557-37-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Bis[di(2-pyridyl)methyl]amine(CAS DataBase Reference)
• NIST Chemistry Reference: Bis[di(2-pyridyl)methyl]amine(211557-37-8)
• EPA Substance Registry System: Bis[di(2-pyridyl)methyl]amine(211557-37-8)

Safety Data

• Hazardous Substances Data: 211557-37-8(Hazardous Substances Data)

Upstream product

• 19437-26-4 2,2'-dipyridyl ketone 
• 58088-50-9 bis(pyridin-2-yl)methylamine 

Relevant articles and documents

Synthesis of bis[di(2-pyridyl)methyl]amine (BDPMA) by a novel one-pot multi-step reductive amination with molecular sieves and Zn/iPrOH

Bis[di(2-pyridyl)methyl]amine (BDPMA) has been synthesized by refluxing di-2-pyridyl ketone and di-(2-pyridyl)methylamine in isopropanol in the presence of molecular sieves and acetic acid and subsequent reduction with zinc dust. The established methods for reductive amination, i.e. NaBH3CN, NaBH(OAc)3 and NaBH4, failed in the synthesis of BDPMA due to a disfavored equilibrium towards the imine formation and therefore long reaction times were required, involving side reactions. The presented method can be used on large-scales and tolerates aromatic heterocycles as functional groups.