211735-76-1 Usage
Description
Farampator is a compound that acts as an AMPA receptor potentiator and glycine reuptake inhibitor. It has demonstrated potential anti-psychotic efficacy and the ability to enhance prefrontal glutamatergic transmission. Its effects on both AMPA-PAMs and GlyT-1 inhibitor may also improve cognitive impairments in schizophrenia, particularly when combined with Risperidone (R525000).
Uses
Used in Pharmaceutical Industry:
Farampator is used as an anti-psychotic agent for its potential efficacy in treating schizophrenia and enhancing prefrontal glutamatergic transmission. Its combination with Risperidone (R525000) may further improve cognitive impairments in patients with schizophrenia.
Used in Neurological Applications:
Farampator is used as a cognitive enhancer to improve cognitive impairments in schizophrenia by modulating AMPA-PAMs and GlyT-1 inhibitor effects. This dual action may provide a more comprehensive approach to managing the symptoms of the disorder.
Check Digit Verification of cas no
The CAS Registry Mumber 211735-76-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,1,7,3 and 5 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 211735-76:
(8*2)+(7*1)+(6*1)+(5*7)+(4*3)+(3*5)+(2*7)+(1*6)=111
111 % 10 = 1
So 211735-76-1 is a valid CAS Registry Number.
211735-76-1Relevant articles and documents
Catalytic amidation of unactivated ester derivatives mediated by trifluoroethanol
Caldwell, Nicola,Jamieson, Craig,Simpson, Iain,Watson, Allan J. B.
supporting information, p. 9495 - 9498 (2015/06/08)
A catalytic amidation method has been developed, employing 2,2,2-trifluoroethanol to facilitate condensation of unactivated esters and amines, enabling the synthesis of a range of amide products in good to excellent yields. Mechanistic studies indicate the reaction proceeds through a trifluoroethanol-derived active ester intermediate.
Benzofurazan compounds for enhancing glutamatergic synaptic responses
-
, (2008/06/13)
Compounds of the general structural formula are shown to have AMPA receptor enhancing properties. The compounds are useful for such therapeutic purposes as facilitating the learning of behaviors dependent upon AMPA receptors, and in treating conditions, such as memory impairment, in which AMPA receptors, or synapses utilizing these receptors, are reduced in numbers or efficiency. They may also be used to enhance excitatory synaptic activity in order to restore an imbalance between brain subregions, as in treatment of schizophrenia or schizophreniform behavior.
