212142-18-2 Usage
Description
Vatalanib succinate, also known as PTK787, is a succinate salt derived from the combination of vatalanib with one molar equivalent of succinic acid. It is a multi-targeted tyrosine kinase inhibitor that targets all isoforms of VEGFR, PDGFR, and c-Kit. Vatalanib succinate is a promising pharmaceutical candidate for various applications due to its ability to inhibit multiple tyrosine kinase receptors, which play a crucial role in tumor angiogenesis and growth.
Uses
Used in Pharmaceutical Industry:
Vatalanib succinate is used as an anti-cancer agent for its ability to inhibit vascular endothelial growth factor receptor (VEGFR), platelet-derived growth factor receptor (PDGFR), and c-Kit tyrosine kinases. By targeting these receptors, it can effectively suppress tumor angiogenesis and growth, making it a potential therapeutic option for various types of cancer.
Used in Drug Development:
Vatalanib succinate is used as a research tool in the development of new drugs targeting tyrosine kinase receptors. Its multi-targeted nature allows researchers to study the effects of inhibiting multiple receptors simultaneously, which can lead to a better understanding of the complex signaling pathways involved in cancer progression and the development of more effective treatment strategies.
Used in Cancer Treatment:
Vatalanib succinate is used as a component in combination therapies for cancer treatment. Its ability to inhibit multiple tyrosine kinase receptors can enhance the efficacy of conventional chemotherapeutic drugs, potentially overcoming resistance and improving patient outcomes.
Check Digit Verification of cas no
The CAS Registry Mumber 212142-18-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,2,1,4 and 2 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 212142-18:
(8*2)+(7*1)+(6*2)+(5*1)+(4*4)+(3*2)+(2*1)+(1*8)=72
72 % 10 = 2
So 212142-18-2 is a valid CAS Registry Number.
InChI:InChI=1/C20H15ClN4.C4H6O4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14;5-3(6)1-2-4(7)8/h1-12H,13H2,(H,23,25);1-2H2,(H,5,6)(H,7,8)
