212838-70-5

Basic information

• Product Name: D-(-)-2-CHLOROPHENYLGLYCINE METHYL ESTER HCL
• Synonyms: D-(-)-2-CHLOROPHENYLGLYCINE METHYL ESTER HCL;D-(-)-2-Chlorophenylglycine methyl ester hydrochloride;(R)-Methyl 2-aMino-2-(2-chlorophenyl)acetate hydrochloride;R-2-Chlorophenylglycine methyl ester hydrochloride (1:1)
• CAS NO: 212838-70-5
• Molecular Formula: C9H11Cl2NO2
• Molecular Weight: 236.1
• EINECS: 1308068-626-2
• Mol File: 212838-70-5.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: D-(-)-2-CHLOROPHENYLGLYCINE METHYL ESTER HCL(CAS DataBase Reference)
• NIST Chemistry Reference: D-(-)-2-CHLOROPHENYLGLYCINE METHYL ESTER HCL(212838-70-5)
• EPA Substance Registry System: D-(-)-2-CHLOROPHENYLGLYCINE METHYL ESTER HCL(212838-70-5)

Safety Data

• Hazardous Substances Data: 212838-70-5(Hazardous Substances Data)

Usage

General Description

D-(-)-2-Chlorophenylglycine methyl ester HCL is a chemical compound that is often used in pharmaceutical research and development. It is an ester of the amino acid 2-chlorophenylglycine and is typically found in a hydrochloride salt form. D-(-)-2-CHLOROPHENYLGLYCINE METHYL ESTER HCL has been studied for its potential therapeutic properties, particularly in the treatment of certain medical conditions such as schizophrenia, anxiety disorders, and other mental health disorders. It is also used as a building block in the synthesis of various pharmaceutical drugs. D-(-)-2-Chlorophenylglycine methyl ester HCL is an important intermediate in the production of many medications and is a valuable tool for scientists and researchers in the pharmaceutical industry.

Upstream product

• 141109-14-0 methyl (S)-(+)-2-amino-2-(2-chlorophenyl)acetate 
• 86169-24-6 2-amino-(2-chlorophenyl)ethanoic acid 
• 67-56-1 methanol 

Downstream Products

• 1446282-66-1 methyl (S)-2-(2-chlorophenyl)-2-(perfluorophenylsulfonamido)acetate 
• 1276118-81-0 C₁₆H₁₄ClNO₂ 

Relevant articles and documents

Isotopically Directed Symmetry Breaking and Enantioenrichment in Attrition-Enhanced Deracemization

The evolution of homochirality via attrition-enhanced deracemization (AED) of enantiomorphic solids is carried out using molecules that differ only in the isotopic composition of a phenyl group positioned remote from the chiral center. Enantioenrichment c

Discovery of novel 2-(3-(2-chlorophenyl)pyrazin-2-ylthio)-N-arylacetamides as potent HIV-1 inhibitors using a structure-based bioisosterism approach

The present work is an extension of our ongoing efforts towards the development and identification of new molecules with anti-HIV activity which have previously led to the discovery of arylazolylthioacetanilides as highly active NNRTIs. In this article, a series of 2-2-(3-(2-chlorophenyl)pyrazin-2- ylthio)-N-arylacetamide derivatives were synthesized and evaluated for in vitro anti-HIV activity. Most of the tested compounds exhibited moderate activities against wild-type HIV-1. Among them, compound 6k showed significant activity against wild-type HIV-1 with an EC50 value of 1.7 μM, along with moderate activity against wild-type reverse transcriptase (RT). The preliminary structure-activity relationship (SAR) and docking calculations of this new series of compounds were also investigated, which may help designing more potent molecules.