214748-65-9

Basic information

• Product Name: 8-ISO-15(R)-PROSTAGLANDIN F2ALPHA
• Synonyms: 8-ISO-15-EPI PROSTAGLANDIN F2ALPHA;8-ISO-15(R)-PROSTAGLANDIN F2ALPHA;9ALPHA,11ALPHA,15R-TRIHYDROXY-(8BETA)-PROSTA-5Z,13E-DIEN-1-OIC ACID;8-iso-15(R)-Prostaglandin F2α;PXGPLTODNUVGFL-PGWUFSIFSA-N
• CAS NO: 214748-65-9
• Molecular Formula: C20H34O5
• Molecular Weight: 354.48
• Mol File: 214748-65-9.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 8-ISO-15(R)-PROSTAGLANDIN F2ALPHA(CAS DataBase Reference)
• NIST Chemistry Reference: 8-ISO-15(R)-PROSTAGLANDIN F2ALPHA(214748-65-9)
• EPA Substance Registry System: 8-ISO-15(R)-PROSTAGLANDIN F2ALPHA(214748-65-9)

Safety Data

• Hazardous Substances Data: 214748-65-9(Hazardous Substances Data)

Usage

Description

8-ISO-15(R)-PROSTAGLANDIN F2ALPHA, also known as 8-iso-15(R) PGF2α, is a member of the prostaglandin-like eicosanoids family. It is formed through the free radical peroxidation of arachidonic acid in membrane phospholipids. As the C-15 epimer of 8-iso PGF2α, it is the only isoprostane isomer that has been extensively studied in various biological systems.

Uses

Used in Pharmaceutical Industry:
8-ISO-15(R)-PROSTAGLANDIN F2ALPHA is used as a biomarker for oxidative stress and lipid peroxidation in the pharmaceutical industry. Its presence in biological systems is indicative of the extent of oxidative stress, which can be associated with various diseases and conditions.
Used in Research and Development:
In the field of research and development, 8-ISO-15(R)-PROSTAGLANDIN F2ALPHA serves as a valuable tool for studying the mechanisms of oxidative stress and its role in the pathogenesis of various diseases. This understanding can lead to the development of novel therapeutic strategies and interventions.
Used in Diagnostic Applications:
8-ISO-15(R)-PROSTAGLANDIN F2ALPHA is utilized as a diagnostic marker to assess the level of oxidative stress in patients. This can help in the early detection of diseases and conditions related to oxidative stress, enabling timely medical intervention and treatment.
Used in Toxicology Studies:
In toxicology, 8-ISO-15(R)-PROSTAGLANDIN F2ALPHA is employed to evaluate the potential toxic effects of various substances on biological systems. By measuring the levels of this isoprostane isomer, researchers can determine the extent of oxidative stress caused by exposure to toxins and environmental pollutants.
Used in Nutritional Science:
8-ISO-15(R)-PROSTAGLANDIN F2ALPHA is also used in nutritional science to study the effects of diet and nutritional supplements on oxidative stress. This can help in the development of dietary recommendations and supplements that promote overall health and reduce the risk of diseases associated with oxidative stress.