21578-99-4

Basic information

• Product Name: Oxirane, trimethylphenyl-
• CAS NO: 21578-99-4
• Molecular Formula: C11H14O
• Molecular Weight: 162.232
• Mol File: 21578-99-4.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: Oxirane, trimethylphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Oxirane, trimethylphenyl-(21578-99-4)
• EPA Substance Registry System: Oxirane, trimethylphenyl-(21578-99-4)

Safety Data

• Hazardous Substances Data: 21578-99-4(Hazardous Substances Data)

Upstream product

• 769-57-3 α,β,β-trimethylstyrene 
• 186594-76-3 (1-tert-Butylperoxy-1,2-dimethyl-propyl)-benzene 

Downstream Products

• 770-85-4 2-methyl-2-phenylbutan-3-one 
• 1231253-32-9 (RS)-2-methyl-3-fluoro-3-phenylbutan-2-ol 
• 78805-31-9 2-methyl-3-phenyl-2,3-butanediol 
• 3280-08-8 2-methyl-3-phenyl-butan-2-ol 
• 62837-59-6 1,2-dimethyl-1-phenyl-1-propanol 
• 29290-99-1 2-methyl-3-phenylbut-1-en-3-ol 
• 25982-72-3 2-methyl-3-phenyl-but-3-en-2-ol 

Relevant articles and documents

Rhenium complex-catalyzed Meinwald rearrangement reactions of oxiranes

The Meinwald rearrangement reaction of oxiranes to the corresponding carbonyl compounds is efficiently catalyzed by the ReBr(CO)5 complex.

Process for the ruthenium-catalysed epoxidation of olefins by means of hydrogen peroxide

The present invention relates to a process for the epoxidation of olefins using catalysts based on ruthenium complexes in the presence of hydrogen peroxide.

Probing competitive enantioselective approach vectors operating in the Jacobsen-Katsuki epoxidation: A kinetic study of methyl-substituted styrenes

This paper describes a study of reactivity and enantioselectivity for a series of methyl-substituted styrenes in the Jacobsen-Katsuki (Mn(salen)-catalyzed) epoxidation reaction. Competition experiments provided kinetic data for the reactivity of the seven possible methyl-substituted styrenes (mono-, di- and trisubstituted) relative to styrene itself, ee values were measured by chiral GC, and absolute configurations were secured by chemical correlation. Of particular interest was the switch in absolute configuration at the benzylic position of the epoxides derived from (Z)- and (E)-α,β-dimethylstyrene, respectively. The results could be rationalized in terms of an approach vector with the phenyl substituent proximal to the salen. As opposed to alkyl groups, a proximal phenyl group has very little effect on the rate of the reaction. Consideration of distal vs proximal approach allows prediction of absolute stereochemistry as a function of alkene substitution pattern. Trisubstituted alkenes with one phenyl group cis to the alkene hydrogen can be identified as a favored substrate class in the title reaction, with both rate and selectivity close to the classic (Z)-β-substituted styrene substrates.