2160-63-6

Basic information

• Product Name: 5-BROMOTHIOPHENE-2-CARBOXALDEHYDE OXIME
• Synonyms: 5-bromo-2-thiophenaldoxime;5-bromo-2-thiophenecarboxaldehydeoxime;5-bromo-2-thiophenecarboxaldehydoxime;BUTTPARK 147\18-66;5-BROMOTHIOPHENE-2-CARBOXALDEHYDE OXIME;5-bromothiophene-2-carbaldehyde oxime;5-Bromothiophene-2-carboxaldoxime, 97%;N-[(5-bromothiophen-2-yl)methylidene]hydroxylamine
• CAS NO: 2160-63-6
• Molecular Formula: C5H4BrNOS
• Molecular Weight: 206.06
• Mol File: 2160-63-6.mol
• Article Data: 6

Chemical Properties

• Melting Point: 132-134℃
• Boiling Point: 272.2°Cat760mmHg
• Flash Point: 118.4°C
• Appearance: /
• Density: 1.81g/cm³
• Vapor Pressure: 0.00302mmHg at 25°C
• Refractive Index: 1.669
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 10.33±0.10(Predicted)
• CAS DataBase Reference: 5-BROMOTHIOPHENE-2-CARBOXALDEHYDE OXIME(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMOTHIOPHENE-2-CARBOXALDEHYDE OXIME(2160-63-6)
• EPA Substance Registry System: 5-BROMOTHIOPHENE-2-CARBOXALDEHYDE OXIME(2160-63-6)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 2160-63-6(Hazardous Substances Data)

Usage

General Description

5-Bromothiophene-2-carboxaldehyde oxime is a chemical compound with a molecular formula of C5H4BrNOS. This substance belongs to the group of organobromine compounds, which are organic compounds that contain carbons linked to bromine atoms. It also falls under the category of oximes, compounds that feature a carbon-nitrogen double bond with another oxygen atom connected to the nitrogen. 5-Bromothiophene-2-carboxaldehyde oxime is typically used in scientific research, particularly in the synthesis of more complex chemical compounds. It's important to handle this substance with caution as its health effects are not fully known.

InChI:InChI=1/C5H4BrNOS/c6-5-2-1-4(9-5)3-7-8/h1-3,8H/b7-3-

Upstream product

• 4701-17-1 5-bromo-2-thiophencarboxaldehyde 

Downstream Products

• 76371-66-9 5-bromo-2-thiophene carboxamide 

Relevant articles and documents

Design, synthesis and in vitro activity of phidianidine B derivatives as novel PTP1B inhibitors with specific selectivity

A series of phidianidine B derivatives were synthesized by introducing various heterocyclic rings. Their inhibitory effects on PTP1B and other PTPs (TCPTP, SHP1, SHP2 and LAR) were evaluated. A majority of them displayed significant inhibitory potency and specific selectivity over PTP1B. The SAR and molecular docking analysis were also described.

A practical and cost-efficient, one-pot conversion of aldehydes into nitriles mediated by 'activated DMSO'

Participation of activated DMSO in the one-pot transformation of aldehydes to nitriles has been described by reacting aldehydes with NHHHCl in DMSO in the absence of any added base or catalyst. The method is applicable to access a wide range of aromatic, heterocyclic, and aliphatic nitriles, in which only water is a byproduct. A straightforward and practical procedure is demonstrated on a multigram scale. Georg Thieme Verlag Stuttgart - New York.

OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS

The present invention relates to certain substituted phenyl oxazolidinones of formula (I) and to processes for the synthesis of the same. This invention also relates to pharmaceutical compositions containing such compounds as antimicrobials. The compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria such as multiple-resistant staphylococci, streptococci and enterococci as well as anaerobic organisms such as Bacterioides spp. and Clostridia spp. species, and acid-fast organisms such as Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium spp.